Identification of genes responsible for familial predispositions to haematological malignancies

一个成功的方法来识别癌症基因已经研究了5-10%的情况下，发生在家庭与遗传易感性发展癌症。与实体瘤相比，血液系统癌症中几乎没有发现致癌的生殖系突变。我们正在使用尖端技术来识别澳大利亚和国际家庭中的血癌基因，并将其与类似的散发性癌症进行比较。

A successful approach to the identification of cancer genes has been to study the 5-10% of cases that occur in families with an inherited predisposition to develop cancer. In contrast to solid tumors, few cancer-causing germ-line mutations have been identified for hematological cancers. We are using cutting edge technologies to identify blood cancer genes in a collection of both Australian and international families and comparing them to similar sporadic cancers.