CELL MIGRATION CONSORTIUM PROJECT

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 相关显微镜的主要目标是开发一个工具箱，用于分析图像序列：a）使用光栅图像相关（RICS）和TIRF时间相关显微术提取蛋白质结合动力学，B）通过两种颜色互相关方法鉴定分子缔合，c）通过模拟信号的强度亮度分析确定蛋白质聚集状态，以及d）开发用于测量粘附组装和拆卸速率以及运动的速率和方向的空间-时间相关性分析。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary goals for correlation microscopy are to develop a toolbox for analyzing image sequences for: a) extracting protein binding dynamics using raster image correlation (RICS) and TIRF time correlation microscopy, b) identifying molecular associations by two color cross-correlation methods, c) determining protein aggregation states by intensity brightness analysis of analog signals, and d) developing spatial-temporal correlation analyses for measuring adhesion assembly and disassembly rates and rates and directions of movement.