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中文摘要
翻译
数学推理能力的成熟是人类认知和学术发展的标志
英文摘要
The maturation of mathematical reasoning skills is a hallmark of human cognitive and academic development. Cognitive, developmental, educational and clinical psychologists have provided valuable insights into the complex and dynamic developmental changes in mathematical skills during childhood. The ages between 7 and 10 (grades 2, 3 and 4) represent an important period for the development of mathematical skills. However, very little is currently known about the development of brain systems that mediate mathematical skill acquisition. The overarching goal of our proposal is to investigate the development of mathematical skills in children using a cognitive and systems neuroscience approach, and a longitudinal study design. The specific aims of this clinical research proposal are to (1) Investigate longitudinal changes in cognitive and brain processes mediating mathematical cognition at grade 4, (2) Investigate longitudinal changes in functional and structural connectivity of brain networks underlying mathematical cognition, and (3) Investigate the cognitive and neural basis of individual differences in mathematical skill development. Our proposed studies will provide important insights into (1) the neural basis of functional specialization for mathematical cognition; (2) the relation between neural changes and changes in working memory, strategy and increased task proficiency; (3) the developmental origins of functional specialization in the posterior parietal cortex; (4) cortical networks and interactions that subserve mathematical task performance at different stages of skill development; and (5) cognitive and neural factors that mediate individual differences in learning. Taken together, this work will provide significant new information on the maturation of brain networks important for mathematical cognition and skill acquisition. This work has the potential to have broad impact on developmental cognitive neuroscience, brain development, and clinical psychology.
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Circuit Mechanisms Governing the Default Mode Network
Circuit Mechanisms Governing the Default Mode Network
Integrative computational models of latent behavioral and neural constructs in children: a longitudinal developmental big-data approach
  • 批准号:
    10200653
  • 项目类别:
  • 资助金额:
    $78.31万
  • 财政年份:
    2019
  • 负责人:
    VINOD MENON
  • 依托单位:
Integrative computational models of latent behavioral and neural constructs in children: a longitudinal developmental big-data approach
  • 批准号:
    10631143
  • 项目类别:
  • 资助金额:
    $78.31万
  • 财政年份:
    2019
  • 负责人:
    VINOD MENON
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: