WASHINGTON UNIVERSITY CER MENTORED CAREER DEVELOPMENT AWARD KM1

描述（由申请人提供）：华盛顿大学（WU）医学院与美国最大和最多样化的非营利卫生系统之一BJC Healthcare有联系，其中包括两家"十大"教学医院;巴恩斯犹太医院和圣路易斯儿童医院。WU是研究，研究培训和临床护理的优秀环境。我们正在申请一个机构比较有效性研究（CER）指导职业发展奖（KM1）（RFA-OD-10 - 011）在吴扩大劳动力能够执行CER。我们将利用WU现有的基础设施，包括临床研究培训中心，公共卫生研究所和临床与转化科学研究所，制定和实施新的CER职业发展计划。我们提出以下具体目标：1。使用研究数据、管理数据和电子健康记录，开发和实施有指导的实践CER培训经验。为来自不同学科的CER学者和其他研究者提供CER培训机会。 2.在华盛顿大学现有的临床研究科学硕士（MSCI）学位和新的人口健康科学硕士（MSPH）学位中开发和实施新的CER课程、课程和短期培训。 3.在华盛顿大学的临床研究培训中心创建六个新的CER学者职位，以支持博士后研究员和专注于CER的初级和中级职业教师。CER学者将参加指导实践CER经验，教学课程和培训，以扩大和加强CER劳动力4。建立一个全面的系统来评估CER职业发展计划。我们将评估学者，教师，导师和培训使用真实的时间调查和输入从外部顾问委员会。 该计划对加强CER员工队伍的长期影响将通过跟踪CER学者和其他参与CER培训的人员在未来10年内的摘要、出版物、赠款和职业发展来衡量。WU拥有优秀的教师，导师和基础设施，以支持这个新的CER职业发展计划和优秀的潜在学者。在WU建立这个新的CER职业发展计划将扩大和加强有资格执行CER的研究人员库，以确定在真实的世界环境中使用的最佳治疗，药物和程序，以改善公共卫生和降低医疗成本。 公共卫生相关性：该补助金为来自不同学科的研究人员提供受保护的时间，工资支持和研究培训，以获得比较有效性研究的专业技能。这些训练有素的研究人员将进行研究，以确定真实的世界环境中患者的最佳治疗，测试和程序，这将改善健康结果并降低不必要或无效治疗的成本。比较有效性研究将提供重要的新知识，告知患者，提供者和支付者哪些治疗和程序对哪些患者最有效。

DESCRIPTION (provided by applicant): Washington University (WU) School of Medicine is linked with BJC Healthcare, one of the largest and most diverse non-profit health systems in the U.S including two "top 10" teaching hospitals; Barnes Jewish Hospital and St. Louis Children's Hospital. WU is an outstanding environment for research, research training, and clinical care. We are applying for an Institutional Comparative Effectiveness Research (CER) Mentored Career Development Award (KM1) (RFA-OD-10-011) at WU to expand the workforce capable of performing CER. We will use existing infrastructure at WU including the Center for Clinical Research Training, Institute of Public Health and Institute for Clinical and Translational Sciences to develop and implement a new CER Career Development Program. We propose the following Specific Aims: 1. Develop and implement mentored hands-on CER training experiences using research data, administrative data, and electronic health records. Provide CER training opportunities to CER scholars and other investigators from diverse disciplines. 2. Develop and implement new CER curricula, classes, and short term training in the existing Masters of Science in Clinical Investigation (MSCI) degree and the new Masters of Science in Population Health (MSPH) degree at Washington University. 3. Create six new CER scholar positions in the Clinical Research Training Center at Washington University to support postdoctoral fellows and junior and mid career faculty focused on CER. CER scholars will participate in mentored hands-on CER experiences, didactic coursework and training to expand and strengthen the CER workforce 4. Establish a comprehensive system to evaluate the CER Career Development Program. We will evaluate scholars, faculty, mentors and training using real time surveys and input from an external advisory board. The long term impact of this program to strengthen the CER workforce will be measured by tracking abstracts, publications, grants and career development of the CER scholars and others participating in the CER training over the next 10 years. WU has excellent faculty, mentors and infrastructure to support this new CER Career Development Program and an outstanding pool of potential scholars. Establishing this new CER Career Development Program at WU will expand and enhance the pool of investigators qualified to perform CER to identify the best treatments, drugs and procedures to use in real world settings to improve public health and reduce healthcare costs. PUBLIC HEALTH RELEVANCE: This grant provides protected time, salary support, and research training for investigators from diverse disciplines to obtain specialized skills in comparative effectiveness research. These well trained investigators will conduct research to determine the best treatments, tests and procedures for patients in real world settings which will improve health outcomes and reduces costs for unnecessary or ineffective treatments. Comparative effectiveness research will provide important new knowledge to inform patients, providers and payers about which treatments and procedures work best in which patients.