Understanding and Preventing Early Adult Drug Abuse

描述（由申请人提供）：本申请提出对999名多民族青年样本进行纵向随访，直至成年。青年评估将包括对药物滥用、犯罪、不安全的性行为和其他已知导致严重适应不良的风险因素（包括艾滋病毒/艾滋病和心理疾病）的面谈和问卷测量。这个样本最初是从三所公立学校的六年级学生中招募的。青少年和他们的家庭在个人层面被随机分配到青少年过渡计划（ATP），这是一个多层次的，以家庭为中心的干预，嵌入在公立学校环境的操作系统中（Dishion & Kavanagh, 2003），或者是一个没有治疗的对照组。参与研究的青少年最初在六年级、七年级和八年级进行评估，使用自我报告调查、同伴提名、教师评分和学校记录，以及九年级的自我报告调查。观察到的家庭和同伴互动的录像带；包括青少年、家长和教师报告在内的多主体评估系统；青少年法庭的记录也被收集起来。目标青少年也进行了CIDI诊断性访谈。本阶段研究的目标是通过实现以下两个目标来扩大我们对青少年和年轻人药物滥用和其他相关问题行为的发病和升级的病因学的理解：(1)评估和报告ATP干预的参与、调解和长期有效性的模式；(2)基于与第一个目标相关的分析获得的信息，完善和测试药物滥用、问题行为、艾滋病毒/艾滋病风险行为和年轻人精神病理的生态模型。据推测，获得的有关治疗效果的信息，无论是积极的、消极的还是中性的，将有助于增加我们对与成年早期不良结果相关的机制的集体理解，以及我们对谁从ATP等预防项目中受益、谁没有受益的认识。

DESCRIPTION (provided by applicant): This application proposes a longitudinal follow-up of a multi-ethnic sample of 999 youth into young adulthood. Young adult assessments will include interview and questionnaire measurement of drug abuse, criminality, unsafe sexual behaviors, and other risk factors known to contribute to serious maladjustment including HIV/AIDS and psychological illness. This sample was originally recruited from 6th graders at three public schools. Youth and their families were randomized at the individual level to the Adolescent Transitions Program (ATP), a multilevel, family-centered intervention embedded within the operating system of the public school environment (Dishion & Kavanagh, 2003), or to a no treatment control group. Participating youth were originally assessed in 6th, 7th, and 8th grades using self-report surveys, peer nominations, teacher ratings, and school records, as well as self-report surveys in the 9th grade. Videotapes of observed family and peer interactions; a multi-agent assessment battery including youth, parent, and teacher reports; and youth court records were also collected. Target youth also were administered the CIDI diagnostic interview. The goal of this phase of research is to expand our understanding of the etiology of the onset and escalation of adolescent and young adult drug abuse and other related problem behaviors by accomplishing the following two objectives: (1) evaluate and report the patterns of engagement, mediation, and long-term effectiveness of the ATP intervention; and (2) refine and test an ecological model of drug abuse, problem behavior, HIV/AIDS risk behavior, and young adult psychopathology based on information obtained from the analyses related to the first objective. It is hypothesized that information gained about treatment effects, whether positive, negative, or neutral will serve to increase our collective understanding of the mechanisms related to poor early adult outcomes and our knowledge of who benefits from prevention programs such as the ATP and who does not.