Liver Disease and HIV

描述（由申请人提供）： 在能够获得有效抗逆转录病毒疗法的国家，肝病已成为艾滋病毒感染者发病率/死亡率的主要原因。原因是复杂的，与共病病因有关，包括丙型肝炎病毒（HCV）和B肝炎病毒（HBV）感染以及药物诱导的肝毒性。研究和信息共享仍然沿着专业线分散。为了改善沟通，促进研究议程，并发展新的富有成效的合作，我们建议继续举办一系列关于艾滋病毒和肝病的国家/国际会议。拟议的会议将于2008年和2010年举行，为期三天，将汇集该领域的主要专家。此外，还将鼓励年轻的调查员和受训人员通过本报告提议的奖学金机制参加培训。预期的会议成果包括提供继续医学教育学分，编写关于该主题的出版手稿，以及提供一个基于网络的教育网站。将特别注意发展新的研究概念和建立合作协会。肝病已成为人类免疫缺陷病毒（HIV）感染者的一个重要问题。该提案描述了一个国家/国际论坛的继续，该论坛汇集了该领域的美国和国际专家，以审查最新的信息，并制定减少这些患者肝脏疾病的研究策略。

DESCRIPTION (provided by applicant): Liver disease has emerged as major contributor to morbidity/mortality among those with HIV in countries with access to effective antiretroviral therapies. The causes are complex and are tied to comorbid etiologies that include hepatitis C virus (HCV) and hepatitis B virus (HBV) infection as well as drug-induced liver toxicity. Research and information sharing remain fragmented along specialty lines. In an effort to improve communication, stimulate the research agenda, and develop new productive collaborations, we propose the continuation of a series of national/international conferences on HIV and liver disease. The proposed conferences will take place over a three day period in 2008 and 2010, and will bring together leading experts in the field. In addition, young investigators and trainees will be encouraged to attend via a scholarship mechanism proposed herein. Expected meeting outcomes include provision of continuing medical education credit, development of a published manuscript on the subject, and the availability of a web-based educational site. Particular attention will be paid to development of new research concepts and establishment of collaborative associations. Liver disease has become an important problem among people infected with the human immunodeficiency virus (HIV). This proposal describes continuation of a national/international forum bringing together U.S. and international experts in the field to review the most current information and to develop research strategies that will reduce liver disease in these patients.