UNC Mentored Career Development Program in Comparative Effectiveness Research

描述（由申请人提供）：比较有效性研究（CER）在今天的美国是至关重要的，因为它被视为医疗改革的核心。为了满足当前和未来的CER需求，需要训练有素的研究人员，他们拥有方法技能和实质性知识，可以进行创新研究，为使用CER做出决策的不同利益相关者（例如，联邦和州政府机构、付款人、雇主和公民）提供信息。北卡罗来纳大学CER K12项目将确定、提供保护时间、培训和指导有前途的、多样化的、有潜力进行创新CER的初级教师。为此，北卡罗来纳大学CER K12项目将为一批CER学者提供5种核心方法的培训，以促进他们的指导职业发展：(1)随机对照试验；(2)使用二手数据的观察性研究；(3)系统文献综述；(4)决策科学/建模；(5)传播与实施。此外，课程强调对CER至关重要的跨领域技能，包括：(1)跨学科团队合作；(2)利益相关者/决策者关系；(3)行政和临床数据库；(4)电子健康档案与信息学；(5)专业技能（包括道德和负责任的研究行为）。在这些核心研究方法和交叉技能的指导下，我们的CER K12项目将结合必修和可选的教学和体验式学习模式，根据CER学者的个人背景和兴趣量身定制。北卡罗来纳大学是CER K12项目的理想机构，因为：(1)来自校园各个部门的大量优秀初级研究人员，我们可以从中选择CER学者；(2)经验丰富、成功的导师；(3)与其他K12项目有良好的成功历史；(4)强调跨学科研究的文化，这对CER至关重要；(5)来自学校、中心和研究所的强有力的制度支持；(6)建立在北卡罗来纳大学其他K12项目成功基础上的创新课程。我们的CER K12项目将利用学者、导师和资源来培训下一代研究人员，他们进行创新的CER，以改善我们公民的健康。

DESCRIPTION (provided by applicant): Comparative effectiveness research (CER) is critical in the U.S. today because it is viewed as central to health care reform. Meeting the current and future demands of CER requires well-trained investigators who possess the methodological skills and substantive knowledge to conduct innovative studies that inform diverse stakeholders who use CER to make decisions (e.g., federal and state government agencies, payers, employers, and citizens). The UNC CER K12 Program will identify, provide protected time, train, and mentor promising, broadly-diverse junior faculty with the potential to conduct innovative CER. To that end, the UNC CER K12 Program will facilitate the mentored career development of a cohort of CER Scholars by providing them with training in 5 core methodologies: (1) randomized, controlled trials; (2) observational studies that use secondary data; (3) systematic literature reviews; (4) decision sciences/modeling; and (5) dissemination and implementation. In addition, the curriculum emphasizes cross-cutting skills that are critical to CER, including: (1) interdisciplinary teamwork; (2) stakeholder/decision-maker relationships; (3) administrative and clinical databases; (4) electronic health records and informatics; and (5) professional skills (including ethics and the responsible conduct of research). Guided by these core research methodologies and cross-cutting skills, our CER K12 Program will use a combination of required and optional didactic and experiential learning modalities that will be tailored to individual CER Scholars' backgrounds and interests. UNC is an ideal institution for this CER K12 Program due to: (1) a large pool of outstanding junior investigators from Departments across campus from which we can select CER Scholars; (2) experienced and successful mentors; (3) a strong history of success with other K12 programs; (4) a culture that emphasizes interdisciplinary research that is essential to CER; (5) strong institutional support from our Schools, Centers, and Institutes; and (6) an innovative curriculum that builds upon the successes of other K12 Programs at UNC. Our CER K12 Program will capitalize on the Scholars, mentors, and resources to train the next generation of investigators who conduct innovative CER that improves the health of our citizens. PUBLIC HEALTH RELEVANCE: The UNC CER K12 Program seeks to facilitate the mentored career development of outstanding junior investigators to conduct CER. Through mentored, interdisciplinary training, CER Scholars will participate in a curriculum that uses didactic and experiential learning to provide CER Scholars with the training, experience, and mentoring required to become independent investigators who conduct CER that improves the health of our citizens.