Research Training in Allergy and Immunology at Massachusetts General Hospital

描述(由申请者提供)：这是哈佛医学院马萨诸塞州总医院新的过敏/免疫学研究培训项目的重新提交。该培训计划的目标是培训医学博士、医学博士/博士和博士后研究员，以便在过敏/免疫学研究领域从事独立的研究工作。我们的计划将集中于我们在成人和儿童过敏/免疫学方面非常成功的预先存在的临床奖学金，以及我们在基础科学、过敏和免疫学研究方面的强大实验室计划。在过去的五年里，MGH的过敏/免疫学部门发生了重大变化，对我们的培训计划产生了重要影响。在担任过敏/免疫科主任24年后，Kurt Bloch博士退休，2000年，Andrew Luster博士被任命为MGH风湿病、过敏和免疫科(DRI)的新主任。这一新倡议的动力是在医学部内设立一个司，侧重于人类疾病的免疫学和炎症基础。为了实现这一目标，成立了免疫学和炎症性疾病中心(CUD)，作为DRI的一部分，勒斯特博士指导该中心作为该司的基础科学基础。这一过敏/免疫学培训计划的目标是在资深教师的指导下提供有监督的实验室研究，以及通过课程和会议进行免疫学、分子生物学、遗传学和伦理问题的有组织的培训。 我们只包括在麻省理工学院积极参与基础科学免疫学研究的实验室的杰出的、成就卓著的导师。共有8名教职员工作为实验室导师参加了这项过敏/免疫学培训计划，5名教职员工作为临床导师参加了培训计划。这些教职员工的参与为过敏/免疫学研究提供了一个绝佳的培训机会。我们相信，我们已经创建了一个平衡、综合的培训计划，该计划将在过敏/免疫学实验室科学研究方面提供高质量的培训，成功地整合医学和博士学员以及基础科学和临床教师。T32培训计划将对麻省理工学院的过敏/免疫学计划产生巨大影响，对于完成该计划从优秀的临床计划到培养下一代致力于过敏/免疫学研究的内科科学家和博士科学家的计划的转变至关重要。

DESCRIPTION (provided by applicant): This is a resubmission for a new research-training program in Allergy/Immunology at the Massachusetts General Hospital, Harvard Medical School. The goal of this training program is to train MD, MD/PhD and PhD post-doctoral fellows for independent investigative careers in Allergy/Immunology research. Our program will center on our highly successful pre-existing clinical fellowship in Adult and Pediatric Allergy/Immunology and our strong laboratory programs in basic science allergy and immunology research. There have been significant changes in the Allergy/Immunology Unit at the MGH over the last five years with important implications for our training program. After 24 years as Chief of the Allergy/Immunology Unit, Dr. Kurt Bloch retired, and in 2000, Dr. Andrew Luster was appointed Chief of a new Division of Rheumatology, Allergy and Immunology (DRAI) at the MGH. The impetus for this new initiative was to develop a Division within the Department of Medicine that would focus on the immunological and inflammatory basis of human disease. To accomplish this goal, the Center for Immunology and Inflammatory Diseases (CUD) was established, which Dr. Luster directs, as part of the DRAI, to serve as the basic science foundation for the Division. The goal of this Allergy/Immunology training program is to provide supervised laboratory research under the guidance of accomplished faculty members, along with structured training in immunology, molecular biology, genetics and ethical issues through courses and conferences. We have included only outstanding highly accomplished mentors with laboratories at MGH that are actively involved in basic science immunology research. Altogether, eight faculty members participate in this Allergy/Immunology training program as laboratory mentors, and five faculty members participate in the training program as clinical mentors. The participation of these faculty members offers an outstanding training opportunity in Allergy/Immunology research. We believe that we have created a balanced, integrated training program that will offer high quality training in laboratory science research in Allergy/Immunology that successfully integrates both MD and PhD trainees and basic science and clinical faculty. A T32 training program would have a dramatic effect on the Allergy/Immunology program at MGH and is critical to complete the transformation of this program from an excellent clinical program to a program that will produce the next generation of physician-scientists and PhD scientists committed to Allergy/Immunology research.