Recruitment of a Bone and Cancer Early Stage Investigator

描述（由申请人提供）：该项目的目标是通过促进招募一名新的早期研究者到拉什大学医学中心担任终身教职，继续发展骨骼和癌症核心中心。医学中心有一大群基础和转化研究人员，他们专注于结缔组织，特别是骨骼、关节软骨、肌腱和韧带。医疗中心的两个重要战略重点领域包括骨科和癌症，一些建筑项目、新招募人员和即将完成的癌症主任招聘证明了这一点。作为…部门之间的合作企业

DESCRIPTION (Provided by the applicant): The goal of this project is to continue the development of a Core Center in Bone and Cancer at Rush University Medical Center by facilitating the recruitment of a new early stage investigator to a tenure-track faculty position. The Medical Center has a large group of basic and translational researchers focusing on connective tissues, particularly bone, articular cartilage and tendons and ligaments. Two important strategic focus areas for the Medical Center include orthopedics and cancer, as evidenced by a number of building projects, new recruits and the nearly completed recruitment of a cancer director. As a cooperative venture between the Department of Anatomy & Cell Biology and the Department of Orthopedic Surgery, we have recently recruited a senior, NIH funded, faculty member with expertise in cancer biology into our newly established bone and cancer program. Through this grant mechanism, we now propose to expand the bone and cancer program by recruiting a laboratory-based early stage investigator who is committed to a career working with clinicians in the design and implementation of translational cancer research. We have already completed the initial search phase and have interviewed three outstanding candidates. Among these candidates, we have prioritized our ranking based on the "fit" between the candidate's research area and expressed desire to have a strong translational component and our clinical and basic science research strengths. The major mission of the Bone and Cancer is to advance patient treatment through improved understanding of cancer survival and metastasis mechanisms. A great deal is now being learned about the potential importance of cancer stem cells in resistance to treatment and the bone microenvironment in bone metastases. The development of a Bone and Cancer Core Center represents an ideal way to bolster cancer research activity at Rush since the great strengths in skeletal research and clinical orthopedic oncology can be leveraged to provide administrative and scientific support for the proposed activities.