SERUM SELENIUM LEVELS AND THYROID CANCER DEVELOPMENT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本横断面病例对照试验旨在确定血清和组织硒浓度与甲状腺癌诊断之间是否存在关联，如果存在，则该关联是否具有性别特异性。将从GUMC的内分泌科、内科和头颈部/部门招募200名来自所有种族组的18-80岁男性和女性（100名已诊断为甲状腺癌; 100名未患甲状腺癌的人将作为对照）。还将从GU组织库收集50份甲状腺癌组织样本和50份对照甲状腺肿或结节性疾病组织样本。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This cross-sectional, case control pilot is to determine if there is an association between serum and tissue concentrations of selenium and the diagnosis of thyroid cancer and if so, if the association is gender specific. 200 men and women age 18-80 from all racial groups will be recruited from the endocrinology, internal medicine, and head and neck divisions/department of GUMC (100 already diagnosed with thyroid cancer; 100 who do not have thyroid cancer will be controls). There will also be 50 thyroid cancer tissue samples and 50 control goiter or nodular disease tissue samples collected from the GU Tissue Repository.