COBRE:OUHSC: IMAGE ACQUISITION & PRODUCTION CORE

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 图像采集和制作模块。所有PJI、ECIs、试点研究人员、他们的导师、模块主任和PI的研究项目都涉及使用该核心。该模块的目的是提供高质量的最先进的仪器和专业知识，以获得光，荧光和Nomarski光学显微图像;以可检索的格式存档图像，提供形态分析和生产出版质量打印。该模块包括600平方英尺的Dean McGee眼科研究所的地下室。该模块设备由光学图像采集设备组成，该设备与三个计算机工作站接口，可访问互联网，用于图像存储、检索、分析和修改，以及用于包埋、切片、组织化学和免疫化学染色的设备。该模块包括一名系统经理和组织学技术员，他们将协助PJrs处理组织和制作图像，或协助操作任何设备。图像采集和制作模块已经在最大能力下运行，用于组织处理，所要求的组织学技术人员将使PJI的项目能够获得优先调度。该模块的服务是最劳动密集型的，将使PJI的更快地获得他们的数据，在更大的数量，分析它，并产生出版质量的图像手稿，海报或Power Point演示文稿。该模块有可能最大限度地提高每个PJI在视觉研究中的生产力，从而加强他们成功竞争未来NIH R 01资金的能力。这反过来不仅会增加俄克拉荷马州视觉研究调查人员的数量，而且会提高研究的质量。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Image Acquisition and Production Module. The research projects of all PJl's, ECIs, Pilot Researchers, their mentors, module directors and PI involve the use of this core. The purpose of this module is to provide quality state of the art instrumentation and expertise to obtain microscopic images with light, fluorescent and Nomarski optics; to archive the images in a retrievable format, to provide for morphometric analysis and to produce publication quality prints. The Module comprises 600sq ft in the basement of the Dean McGee Eye Institute. The Module equipment consists of optical image acquisition devices interfaced with three computer work stations with internet access for image storage, retrieval, analysis and modification as well as equipment for embedding, sectioning, and histochemical and immunochemical staining. The module includes a Systems Manager and histology technicians who will assist the PJrs either in the processing of tissue and production of images, or by providing assistance in the operation of any of the equipment. The Image Acquisition and Production Module is already operating at maximum capacity for tissue processing and the histology technician requested will enable the PJl's projects to be receive priority scheduling. The services of this module are the most labor intensive and will enable the PJl's to obtain their data more rapidly, in greater quantity, to analyze it and to produce publication quality images for manuscripts, posters or Power Point presentations. This Module has the potential to maximize the productivity of each of the PJl's in vision research and thereby strengthen their ability to successfully compete for future NIH R01 funding. This in turn will increase not only the number of Vision Research Investigators in Oklahoma but also the quality of the research.