EFFECT OF BROMODICHLOROMETHANE ON PLACENTAL DEVELOPMENT

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 一些流行病学报告表明，饮用水净化的副产品导致人类晚期流产。环保署现在已经制定了一项计划，要求所有公用事业区通知所有水用户的三卤甲烷浓度在中央来源。 需要进行更多的研究，以确定水龙头的水平、与这些水平相关的风险以及毒性作用的机制。 非人灵长类动物为这类研究提供了唯一合适的动物模型。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Several epidemiology reports have suggested that by-products of drinking water purification results in late term abortion in human populations. EPA has now instituted a program which requires all Public Utility Districts to notify all water users of the trihalomethane concentration at the central source. Additional studies are required to determine levels at the tap, risks associated with those levels and the mechanism(s) of toxic action. The nonhuman primate provides the only appropriate animal model for this kind of study.