Exposure Core

暴露评估核心将负责收集数据，以便对三项健康研究的暴露进行估计。这将包括：1)收集和质量检查空气资源委员会的常规空气监测数据；2)在贝克斯菲尔德的一个中心站点建立多环芳烃(PAHs)和内毒素的采样，并在那里收集和分析样本一年，以建立多环芳烃和内毒素的时间变异性；3)在多个地点收集1-2个月的同时样本；4)探索常规空气污染物、多环芳烃和内毒素的空间变化模式。需要定期收集污染物的数据，以了解社区当前的暴露梯度，这将因空气污染物而异，并有助于项目3的健康影响分析。PM2.5的化学成分将包括元素碳、有机碳、硝酸盐、硫酸盐和痕量金属。此外，2010/201秋冬期间，将在另外两个空气监测站收集为期2个月的多环芳烃数据；2010年夏季，将在另外5个空气监测站收集为期1个月的陆地内毒素样本。正在收集这些数据，以提高对大贝克斯菲尔德地区这些污染物的空间变异性的了解，这对中心的设计至关重要。此区域当前不存在此类型的空间数据。这些暴露数据将被健康研究用作他们为预科中心计划的工作的一部分，但也将指导我们规划中心在满员中心时需要收集的数据。

The Exposure Assessment Core will be responsible for collecting data to enable estimates of exposures for the three health studies. This will include: 1) collecting and quality checking routine air monitoring data from the Air Resources Board; 2) establishing sampling for polycyclic aromatic hydrocarbons (PAHs) and endotoxin at a central site in Bakersfield and collecting and analyzing samples there for one year to establish the temporal variability for PAHs and endotoxin; 3) collecting contemporaneous samples for PAHs and endotoxin at multiple locations for 1-2 months; 4) exploring the varying spatial patterns for routine air pollutants, PAHs and endotoxin. The data for routinely collected pollutants are needed to understand current exposure gradients in the communities, which will differ by air contaminant, and to facilitate health effects analyses for Project 3. The PM2.5 chemical constituents will include elemental carbon, organic carbon, nitrate, sulfate, and trace metals. In addition, PAH data will be collected at two other air monitoring stations for a 2 month period in fall/winter 2010/201 land endotoxin samples will be collected at 5 other air monitoring stations for a 1 month period in summer 2010. These are being collected to improve the understanding of spatial variability of these pollutants in the greater Bakersfield area which is critical to the design of the center. No spatial data of this type currently exist for this area. These exposure data will be used by the health studies as part of their planned work for the pre-center, but will also guide us in planning the data the center will need to collect when it is a full center.