课题基金 / 基金详情

A Preservation and Packaging Platform for Cell and Tissue Based Therapies

A Preservation and Packaging Platform for Cell and Tissue Based Therapies
用于细胞和组织疗法的保存和包装平台
批准号:
TS/G000263/1
负责人:
David John Williams
金额:
$23.95万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2008
资助国家:
英国
项目状态:
已结题
起止时间:
2008 至 --

项目摘要

项目成果

David John Williams的其他基金

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中文摘要
翻译
该项目旨在为基于细胞和组织的疗法创建一个保存和包装平台,使英国公司能够进入欧洲、北美和其他全球市场。传统上,生物实体的保存、储存和运输解决方案主要是以蛋白质为基础的,涉及冷冻干燥(冷冻干燥)和/或冷冻保存。然而,活细胞构成了细胞治疗应用的重要组成部分,迫切需要包装解决方案,以保持细胞的活力和运输后的功能,并在临床上为最终用户提供易用性。可验证的包装平台,允许改善生活产品的保存和保质期,将使英国企业能够从英国网站进入世界市场,并最大限度地提高他们在全球价值链中的份额。该项目将展示人类细胞和组织疗法包装和运输平台的关键组件。
英文摘要
This project aims to create a preservation and packaging platform for cell and tissue based therapies, allowing UK companies to reach the European, North American and other global markets. Traditionally, preservation, storage and transportation solutions for biological entities, mostly protein-based, have involved lyophilisation (freeze drying) and/or cryopreservation. However, living cells constitute an essential part of cell therapy applications and there is a real and urgent need for packaging solutions that preserve cell viability and function post transport, and provide ease-of-use to the end-user in clinic. Validatable packaging platforms that allow improved preservation and shelf life of living products will give UK businesses the capability to reach world markets from UK sites and maximise their share of the global value chain. This project will demonstrate key components of a packaging and shipping platform for human cell and tissue based therapies.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
Scale up and Manufacturing of Cell-Based Therapies
细胞疗法的规模化和制造
DOI: --
发表时间:
期刊:
影响因子: --
作者: [David John Williams (Author)]
通讯作者: David John Williams (Author)
6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore
第六届世界生物力学大会(WCB 2010)。
DOI: 10.1007/978-3-642-14515-5_289
发表时间: 2010
期刊:
影响因子: --
作者: [Nikolaev N]
通讯作者: Nikolaev N
Effect of Cold Storage and Mechnical Vibration on Human Mesenchymal Stem Cell Therapeutic Products Transported in Suspension
冷藏和机械振动对悬浮运输的人间充质干细胞治疗产品的影响
DOI: --
发表时间:
期刊:
影响因子: --
作者: [Nikolay Nikolaev (Author)]
通讯作者: Nikolay Nikolaev (Author)
Effects of Dynamical Mechanical Forces on Human Mesenchymal Stem Cell Therapy Products
动态机械力对人类间充质干细胞治疗产品的影响
DOI: --
发表时间:
期刊:
影响因子: --
作者: [David John Williams (Author)]
通讯作者: David John Williams (Author)
EPSRC-NIHR HTC Partnership Award 'Plus': UNIFY Plus
  • 批准号:
    EP/N027221/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $46.42万
  • 财政年份:
    2016
  • 负责人:
    David John Williams
  • 依托单位:
EPSRC - NIHR Healthcare Technology Co-operative (HTC) Partnership Award - Unify: A network focused on the treatment of fracture non-unions
  • 批准号:
    EP/M000230/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $19.07万
  • 财政年份:
    2014
  • 负责人:
    David John Williams
  • 依托单位:
E-TERM, Engineering Tissue Engineering and Regenerative Medicine
  • 批准号:
    EP/I017801/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $367.57万
  • 财政年份:
    2012
  • 负责人:
    David John Williams
  • 依托单位:
LSI DTCs 2007-Doctoral Training Centre for Regenerative Medicine
  • 批准号:
    EP/F500491/1
  • 项目类别:
    Training Grant
  • 资助金额:
    $911.76万
  • 财政年份:
    2008
  • 负责人:
    David John Williams
  • 依托单位:
海外基金