Informatics

信息学核心构成了项目调查人员寻求技术援助的资源 在研究的所有阶段支持数据管理、统计分析和分析解释 进程。中心调查人员收集的数据来自广泛的来源，包括对 啮齿动物(P2，P4，P5，P6)，灵长类(P2，P3)和人类(P1，P2)，以及各种不同的方法 包括电生理(P3、P4、P5、P6)、动物行为(P3、P4)、神经解剖学(P2、P3、P4、P5、P6)和 人类行为和成像研究(PI)。所有的项目PI都是资深的、有经验的调查人员 在自己感兴趣的领域收集和分析数据方面经验丰富。数据的种类和数量 代表着中心的巨大潜力，但也强调了数据协调的重要性， 整合和共享，以实现中心的目标。这一核心的主要重点将是协助 及时整合和传播跨项目的这些数据，以提高中心的整体目标。确实有 核心C的四个主要任务。第一是确保个人数据的一致性和质量 并将其收集到一个项目调查员可以随时访问的中央储存库中。这个 核心的第二个任务是为统计设计和分析提供密集的协调投入 中心的研究从研究开始到结果的出版和传播。的第三个使命 核心C将是开发跨物种的内侧和眼眶皮质以及它们的计算模型 内囊/纹状体的投射。这些模型将分别基于3-D模型 在P2和核心B中开发，并在P1中进行PET研究。核心的第四个使命是开发时间 将协助解释项目3和项目4中收集的电生理数据的系列分析 高频刺激Vca/S对局域场电位、振荡态和电磁场的影响 大脑皮层单个神经元的群体编码。 相关性(请参阅说明)： 在该中心中，项目之间的数据协调和共享至关重要，因为该中心跨越多个站点 方法论。该核心将管理一个集中的数据存储库，并提供统计和 为中心的个别项目提供计算支持。

The Informatics core constitutes a resource for project investigators seeking assistance with technical support for data management, statistical analyses, and analytic interpretation at all stages of the research process. The data collected by Center investigators comes from a wide range of sources including studies of rodents(P2,P4,P5,P6) primates(P2,P3), and humans(P1,P2), as well as across diverse methodologies including electrophysiologic(P3,P4,P5,P6), animal behavior(P3,P4), neuroanatomic (P2,P3,P4,P5,P6) and human behavior and imaging studies(PI). All of the project Pis are senior, well-established investigators who are experienced in data collection and analysis in their own fields of interest. The variety and volume of data represent enormous potential for the Center but also underscore the importance of data coordination, integration, and sharing to achieve the Center's aims. The primary focus of this core will be to assist in the timely integration and dissemination of this data across projects to enhance overall Center goals. There are four main missions of Core C. The first is to ensure the uniformity and quality of data across the individual projects and to collect them in a central repository that is readily accessible to project investigators. The second mission of the core is to provide intensive coordinated input into the statistical design and analysis of Center studies from study inception through publication and dissemination of results. The third mission of Core C will be to develop computational models across species of medial and orbital cortex and their projections in the internal capsule/striatum. These models will be based respectively on the 3-D models developed in P2 and Core B, and on the PET studies in P1. The fourth mission of the core is to develop time series analyses that will assist in the interpretation of electrophysiological data collected in projects 3 and 4 related to the effects of high frequency VCA/S stimulation on local field potentials, oscillatory states and population coding of individual neurons in cortex. RELEVANCE (See instructions): Data coordination and sharing between projects is critical in this Center that spans multiple sites and diverse methodologies. This Core will manage a centralized data repository as well as provide the statistical and computational support for the individual projects in the Center.