Mayo Clinic Center for Translational Science Activities

马约诊所CTSA的总体目标是致力于建立一个基础广泛的综合性家庭， 马约诊所的临床和康复科学（CTS）将最终改善人类健康。在这 在这种背景下，我们寻求使马约CTSA及其利用的资源成为效率的引擎， 临床和转化研究，同时也是创新的驱动力。我们还寻求整合我们的 地方活动与联合会范围内旨在协调和统一的努力。为了实现我们的目标， 这次更新有六个总体具体目标：目标1 -培养和保持优秀的 多学科临床和转化科学工作者。这支队伍包括 投资者和支持人员。目标2 -消除翻译工作的障碍。这将是 通过以下方式实现：a）在监管和合规性精简方面的集中努力，B）提供 为投资者提供出色的设计、生物制药和道德支持，以及c）进一步整合支持 服务目标3 -与提供者和社区合作，改善医疗保健服务， 社区健康。这包括对基于实践的研究的实质性承诺，社区参与 研究并将比较有效性研究纳入临床实践。目标4 -展开 先进的设施和其他核心资源，以增加临床研究的价值。具有值 在这种情况下定义为质量和成本的quofient，目标是提高质量，降低成本， 为临床和转化研究的全方位提供资源。目标5 -刺激小说 通过有针对性地支持创新试点和可行性研究， 促进新方法的发展。目标6 -利用信息学整合和促进 临床和转化研究。这包含了信息学的广泛观点，包括： 为CTS开发标准化的电子数据采集和分析工具，B）强有力的咨询， 利用马约对电子临床系统的承诺的医学信息学工具，以及c） 生物信息学服务和能力，这将有助于促进“新生物学”在临床上的应用， 和非正式调查。这一愿景完全符合马约诊所的使命：“为了 每天通过综合临床实践，教育和 research. "

The overall goal ofthe Mayo Clinic CTSA is to confinue to build a broad-based and integrated home for clinical and translafional science (CTS) at Mayo Clinic that will ulfimately improve human health. In this context, we seek to make the Mayo CTSA and the resources it leverages both an engine of efficiency for clinical and translational research and at the same fime a driver of innovation. We also seek to integrate our local activities with consortium wide efforts directed at coordination and alignment. To achieve our goal we have six overarching specific aims for this renewal: Aim 1 - Train and maintain an outstanding multidisciplinary clinical and translational sciences workforce. This workforce includes teams of both invesfigators and support staff. Aim 2 - Eliminate barriers to the work of translation. This will be accomplished through a) confinued efforts at regulatory and compliance streamlining, b) provision of outstanding design, biostatisfics, and ethics support for invesfigators, and c) further integration of support services. Aim 3 - Collaborate with providers and communities to improve health care delivery and community health. This includes substantial commitments to practice-based research, communityengaged research and translafing comparative effectiveness research into clinical pracfice. Aim 4 - Deploy advanced facilities and other core resources to increase the value of clinical research. With value defined in this context as the quofient of quality and cost, the goal is to increase quality, decrease costs, and provide resources to the full spectrum of clinical and translational investigafion. Aim 5 - Stimulate novel research directions and methodologies by targeted support of innovative pilot and feasibility studies and fostering the development of novel methodologies. Aim 6 - Employ informatics to integrate and facilitate clinical and translational investigation. This encompasses a broad view of informafics including: a) developing a standardized electronic data capture and analysis tools for CTS, b) robust consultafion and tools for medical informatics that leverage Mayo's commitments to electronic clinical systems, and c) bioinformafics services and capabilities that will help facilitate the applicafion of the "new biology" to clinical and translafional invesfigafion. This vision is enfirely consistent with the stated mission of Mayo Clinic: "To provide the best care to every patient every day through integrated clinical practice, education, and research."