Postdoctoral Research Training in Anesthesiology and Critical Care Medicine

描述（由申请人提供）：麻醉学成功地使术中环境成为一个极其安全的地方，这一成就现已被其他专业认可和模仿，但不应掩盖这样一个事实，即关于整个围手术期经验的重要基本问题仍未得到解答。这些问题涉及1)全麻作用机制，2)围手术期生理状态，3)术后谵妄和认知功能障碍的机制和预防，4)整个围手术期的安全性，5)改善远期预后，6)急性和慢性疼痛的治疗。然而，维持指导麻醉学领域走向未来的科学基础设施，需要一群训练有素、积极进取的专业内科科学家，他们致力于追求麻醉学的重要问题。为了确保麻醉学在科学上的强大未来，约翰霍普金斯大学麻醉学和重症医学系（ACCM）正在提交这份申请，以支持麻醉学博士后研究培训。除了为受训者提供重要的支持之外，预计该项目将继续完善约翰霍普金斯ACCM招募，培训和发展下一代麻醉学专业的内科科学家的方法。ACCM在提供临床和基础麻醉学研究培训方面有着悠久而富有成效的历史，这一培训计划将继续培养和规范化。目前，培训计划支持的优秀学员正在取得积极成果。结合约翰霍普金斯大学已经为教师发展提供的大量资源，麻醉学博士后研究培训基金将继续为培训医师科学家提供一个绝佳的机会，以扩展麻醉学实践的科学基础。

DESCRIPTION (provided by applicant): Anesthesiology's success in making the intraoperative environment an extremely safe place, an accomplishment now recognized and emulated by other specialties, should not obscure the fact that important fundamental questions about the entire perioperative experience remain unanswered. These questions pertain to 1) the mechanism of general anesthetic action, 2) physiology of the perioperative state, 3) the mechanism and prevention of postoperative delirium and cognitive dysfunction, 4) providing safety throughout the entire perioperative period, 5) improving long-term outcomes, and 6) the treatment of acute and chronic pain. However, maintaining the scientific infrastructure that will guide the field of Anesthesiology into the future requires a core of well-trained and motivated physician-scientists within the specialty who are dedicated to the pursuit of problems important to Anesthesiology. To help ensure a scientifically robust future for Anesthesiology, the Department of Anesthesiology and Critical Care Medicine (ACCM) at the Johns Hopkins University is submitting this application to support Postdoctoral Research Training in Anesthesiology. In addition to providing a critical avenue for the support of Trainees, it is anticipated that this program will continue to refine the approach whereby Johns Hopkins ACCM recruits, trains, and develops the next generation of physician-scientists in the specialty of Anesthesiology. ACCM has a long and productive history of providing training in clinical and basic Anesthesiology research, which this Training Program will continue to cultivate and formalize. Positive results are now being realized with the outstanding Trainees currently supported by the Training Program. Combined with the considerable resources already in place for faculty development at Johns Hopkins University, an Anesthesiology Post Doctoral Research Training Grant will continue to provide an outstanding opportunity for training physician-scientists to extend the scientific foundation for the practice of Anesthesiology. PUBLIC HEALTH RELEVANCE: Important fundamental questions exist about anesthesia and the care of patients during and after surgery. The goal of this application is to provide support for the training of physician-scientists to address these important problems and guide the specialty of Anesthesiology into the future.