Training Program in Developmental Biology

描述（由申请人提供）：这是一个竞争性更新的发展生物学前和博士后培训计划。拟议的项目包括来自大学多个学院和部门的教师，并反映了宾夕法尼亚在过去十年中发生的发育生物学研究和培训的重大扩展。培训经验强调实验室研究直接针对胚胎发育的基本机制，利用多种脊椎动物，无脊椎动物和植物生物。它促进了现代遗传、细胞和分子方法在发育研究中的应用。研究训练领域包括转录和细胞信号机制，控制细胞谱系的决定，分化，迁移，器官发生，细胞衰老，形态发生和模式形成。鼓励学员探索临床研究领域，包括癌症和遗传性疾病的发展。为了准备他们的研究训练，博士预科学生在既定的学习课程中接受正式的指导，包括发育生物学的讲座课程和关于发育机制和疾病的遗传、细胞和分子方法的高级研讨会。Pre- and - post-博士生还参加发育生物学杂志俱乐部、研讨会项目、选定主题的研究讨论小组、年度科学专题讨论会和年度静修。学员在地方专题讨论会和国家会议上展示他们的研究成果。这一培训方案的主要目标是为学员在学术和政府机构或生物技术工业中担任发育生物学领域的独立调查员做好准备。

DESCRIPTION (provided by applicant): This is a competitive renewal for a pre- and post-doctoral training program in developmental biology. The proposed program includes faculty from multiple schools and departments within the University, and reflects a major expansion of developmental biology research and training that has occurred at Pennsylvania over the past ten years. The training experience emphasizes laboratory research directed towards basic mechanisms of embryonic development using a diversity of vertebrate, invertebrate, and plant organisms. It fosters the application of modern genetic, cellular, and molecular approaches to developmental studies. Research training areas include transcription and cell signaling mechanisms that control cell lineage determination, differentiation, migration, organogenesis, cellular senescence, morphogenesis, and pattern formation. Trainees are encouraged to explore clinical research areas including cancer and genetic diseases of development. In preparation for their research training, predoctoral students receive formal instruction in an established curriculum of study, including lecture courses in developmental biology and advanced seminars on genetic, cellular, as well as molecular approaches to developmental mechanisms and disease. Pre- and post-doctoral students also participate in developmental biology journal clubs, a seminar program, research discussion groups on selected topics, annual scientific symposia, and a yearly retreat. Trainees present their research findings at local symposia and national conferences. The primary objective of this training program is to prepare trainees for careers as independent investigators in the field of developmental biology in academic and governmental institutions or in the biotechnology industry.