Comprehensive Anesthesia Research Training

描述(由申请者提供)：这项培训资助的目标是确保我们的学员学习最先进的研究技术，以及提出研究问题的基本原理，以及分析数据和总结结果所涉及的批判性思维。培训计划必须培训研究人员制定和撰写赠款。培训计划必须向临床医生传授统计技能和对临床研究中涉及的规则的理解。为了成为多才多艺的临床研究人员，我们将让我们的临床实习生了解基础科学研究，并掌握基础科学研究所涉及的实验室技能。我们已经为我们的教员招募了有才华的基础科学家和内科科学家。我们的目标是增加这些研究人员群体之间的对话，以培养出既能与临床研究人员合作，又能与基础科学研究人员合作的翻译研究人员。我们将我们的教员组织成四个综合的科学轨道：神经科学和麻醉学、重症监护、疼痛和成瘾以及血管生物学和生物工程。我们现在提出了第五个轨道，临床研究培训，它直接与所有四个科学轨道合作。麻醉部的一名高级研究员领导着每一项研究，每项研究都包括内科科学家和基础科学家。这种结构的提出是为了促进富有成效的互动，并在具有共同兴趣的研究人员之间开发项目赠款，同时允许在对麻醉实践重要的不同领域进行培训。与基础科学研究培训计划相比，临床研究培训一直是非正式的，组织较少。因此，该培训计划的使命之一是提供一种适用于动态临床环境的结构化、有组织的临床研究方法教学方法。最终目标是培养学员成为一名独立的临床调查员，他们将在临床研究研究设计方法和分析技术方面受到良好的培训，并在学术研究环境中变得富有成效，为改善患者结果的发现做出贡献。我们要求每年4个主要由博士后研究员填补的职位，为期两年。我们拥有的主要是医学博士和博士，但我们正在努力招募更多的临床科学家，他们将成为医学博士。我们将为他们提供两年的培训。 相关性：越来越多的医生需要将基本的科学发现带给患者，并证明这些发现实际上改善了患者的预后。在患者身上测试药物和设备需要监管知识、关于临床试验设计的知识以及有关发现所涉及的科学知识。这笔培训补助金将培训医生，使他们能够为患者带来更多的科学发现，并仔细记录这些发现的安全性、有效性和重要性。

DESCRIPTION (provided by applicant): The objectives of this training grant are to ensure that our trainees learn state-of-the-art research techniques, as well as the fundamentals of posing a research question, and the critical thinking involved with analyzing data and summarizing results. A training program must train the researchers to formulate and write grants. A training program must teach clinicians the statistical skills and an understanding of the regulations that are involved in clinical research. To become versatile clinical researchers, we will have our clinical trainees acquire an understanding of basic science research and the laboratory skills involved in basic science research. We have recruited talented basic scientists and physician-scientists for our faculty. Our goal is to increase the dialogue between these groups of researchers to produce translational researchers who are capable of working with both clinical researchers and with basic science researchers. We have organized our faculty into four integrated scientific tracks: Neuroscience and Anesthesia, Critical Care, Pain and Addiction, and Vascular Biology and Bioengineering. We are now proposing a fifth track, Clinical Research Training, that directly collaborates with all the four scientific tracks. A senior researcher in the Department of Anesthesia leads each of these tracks and each track includes physician-scientists and basic scientists. This structure is proposed to foster productive interactions and develop program project grants amongst the researchers with common interests, while allowing training in the diverse areas important to the practice of anesthesia. In contrast to basic science research training programs, clinical research training has been informal and less organized. As a result, one of the missions of this training program is to provide a structured, organized approach to teaching clinical research methods, applicable to the dynamic clinical environment. The ultimate goal is to prepare the trainee to become an independent clinical investigator, who will be well trained in clinical research study design methods and analytical techniques and become productive in an academic research environment, contributing to discoveries that will improve patient outcomes. We request 4 slots per year that will primarily be filled with postdoctoral fellows for two years. We have had mostly MD/PhDs and PhDs but we are attempting to recruit more clinician scientists who will be MDs. We will offer them 2 years of training. Relevance: There is an increased need for physicians to bring basic scientific discoveries to patients, and to prove that these discoveries actually improve patient outcomes. Testing medications and devices in patients requires regulatory knowledge, knowledge regarding clinical trial design, and knowledge about the science involved in the discovery. This training grant will train physicians so that they can bring more scientific discoveries to patients and carefully document the safety, efficacy, and importance of the discoveries.