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中文摘要
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描述(由申请人提供): 这项申请请求支持传染病和炎症性疾病的跨部门培训计划,旨在促进优秀医学生进入生物医学研究职业。这一创新的研究丰富计划结合了指导教师的研究专业知识和独特的机构资源,用于医学生的实践培训。培训由来自微生物学和免疫学、生物化学和分子生物学、病理学、内科、儿科和外科的28名项目教职员工提供。研究主题将集中在感染和炎症,特别是病原体的传播,病原体进入部位(呼吸道、皮肤和粘膜)宿主炎症反应的调节,血液、肝脏和其他器官中白细胞迁移的调节,以及控制病原体和组织损伤的疫苗/药物开发。学员将在为期12周的研究期间从事全职工作,并获得深入接触生物学概念和现代生物医学研究领域和工具的机会。他们还将有机会选择基础、临床和转化性或行为研究项目。该项目将为有才华的医学生与NIH资助的研究教师导师牵线搭桥,将日常研究经验与正在进行的一系列课程、夏季研究研讨会、同行圆桌研究讨论、口头演示以及来自UTMB优秀教师的监测相结合。具体目标是:1)让医学生在职业发展早期接触到研究职业的兴奋和挑战,并鼓励他们的调查和分析技能;2)鼓励医学生从事传染病和炎症性疾病领域的基础和临床研究;3)为希望在未来寻求更多研究培训和资金的学生提供宝贵的经验和潜在的参考;以及4)增加从事NIAID使命所需领域的生物医学或行为研究的内科科学家队伍。有机会在国家研讨会和会议期间正式介绍研究成果,并建立了适当的跟踪系统,以监测受训者的职业发展和这一培训方案的成功。
英文摘要
DESCRIPTION (provided by applicant): This application requests support for an interdepartmental training program in Infectious Diseases and Inflammatory Disorders and is designed to promote the entry of outstanding medical students into biomedical research careers. This innovative research enrichment program combines the mentoring faculty's research expertise with unique institutional resources for the hands-on training of medical students. Training is provided by 28 program faculty members from the Departments of Microbiology & Immunology, Biochemistry & Molecular Biology, Pathology, Internal Medicine, Pediatrics, and Surgery. The research theme will be centered on infections and inflammation, especially in terms of transmission of pathogens, regulation of host inflammatory responses at the sites of pathogen entry (airway, skin, and mucosa), regulation of leukocyte migration in the blood, liver and other organs, and vaccine/drug development for the control of pathogens and tissue damage. Trainees will work in full-time positions during a 12-week research period, and receive an in-depth exposure to biological concepts and modern biomedical research areas and tools. They will also have the opportunity to choose basic, clinical, and translational or behavior research projects. The program will match talented medical students with NIH-funded research faculty mentors, coupling the daily research experience with an ongoing series of courses, summer research seminars, peer round-table research discussions, oral presentations, and monitoring from outstanding UTMB faculty. The specific objectives are: 1) to expose medical students early in their career development to the excitement and challenges of a research career and to encourage their investigative and analytical skills, 2) to encourage medical students to pursue a career in basic and clinical research in the areas of infectious diseases and inflammatory disorders, 3) to provide valuable experience and potential references for students who wish to seek additional research training and funding in the future, and 4) to increase the pool of physician scientists engaged in biomedical or behavioral research in those areas necessary for the mission of the NIAID. Opportunities exist for formal presentation of research findings during national symposia and meetings, and an adequate tracking system is in place for monitoring career development of trainees and success of this training program.
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