ADMINISTRATIVE CORE

作为首席调查员，医学博士帕特里夏·K·多纳霍将担任该计划项目的主任，与她的行政核心一起监督和协调这项广泛努力的所有方面。多纳霍博士将设计和规划项目UI，协调项目I、II和III的所有研究，与他们各自的首席调查员以及另外两名核心主管合作。她将协商和协调平台的可用性，与每个地点的每个研究人员密切合作，对选定进行验证的基因进行优先排序和预算， 重新测序，以及选择动物模型或IPS研究进行功能评估。 该计划项目的行政核心将作为“交通管制”，快速有效地与所有计划工作人员沟通，并将任务分配给主任和首席调查员认为适当的地点，并监督和协助实验室工作人员完成任务。站点之间每周的交流将通过直接联系或使用Polycom VSX70005系统的视频会议进行。

As the lead investigator, Patricia K. Donahoe, MD, will serve as the Director of this Program Project to oversee and coordinate, with her Administrative Core, all aspects of this extensive endeavor. Dr. Donahoe will design and plan Project UI, coordinate all research for Projects I, II, and III, with their respective Principal Investigators and with the two other Core Directors. She will negotiate and coordinate platform availability, working closely with each investigator at each site to prioritize and budget genes selected for validation, resequencing, and the choice of animal models or IPS study for functional assessment. The Administrative Core of this Program Project will serve as "traffic control" to quickly and efficiently communicate with all Program staff and assign tasks to the appropriate sites as deemed by the Director and Principal Investigators, and to monitor and assist laboratory staff in their completion. Weekly communications between sites will be done by direct contact or by videoconferencing using a PolyCom VSX70005 system.