HIGH SPEED VOLUMETRIC MRSI WITH ECHO PLANAR K-SPACE TRAJECTORIES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 具有时变梯度编码的人脑的快速质子MR光谱成像（1H-MRSI）具有在临床可接受的时间内产生代谢物图的优点。然而，缺乏标准化的成像，重建和定量方法阻碍了在不同地点的多个平台上进行的研究的比较。为了推广标准的体积MRSI成像方法，需要在3 T的GE MR扫描仪上使用具有水参考的高速MRSI序列。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Fast proton MR spectroscopic imaging (1H-MRSI) of the human brain with time varying gradient encoding has the advantage of producing metabolite maps within clinically acceptable time. However, lack of standardized imaging, reconstruction and quantification methods hinders comparison of studies conducted on multiple platforms at different sites. To promote a standard volumetric MRSI imaging method, a high speed MRSI sequence with water referencing is needed on GE MR scanners at 3T.