MAPPING FINE SCALE OLFACTORY SENSORY REPRESENTATIONS IN THE CORTEX

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这个项目的目的是揭示构成嗅觉处理基础的回路的神经解剖学组织。虽然跨物种的研究揭示了大脑外围高度保守的嗅觉感觉图，但人们对大脑中实现嗅觉编码和感知的回路知之甚少。这个项目的主要目标是绘制小鼠大脑中从鼻子到皮质的输入特定嗅觉回路的连接。因此，这些研究的结果可以应用于识别不同嗅觉输入的皮质整合部位，并剖析嗅觉神经回路形成和功能中基因和经验的相对贡献。这些研究应该对理解恐惧和交配等先天行为有意义，也有助于学习和记忆的研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim of this project is to reveal the neuroanatomical organization of circuits that underlie olfactory processing. While studies across species have revealed highly conserved olfactory sensory maps in the periphery, far less is known about the circuits that enable olfactory coding and perception in the brain. The primary objective of this project is to map the connectivity of input specific olfactory circuits from the nose to the cortex in the mouse brain. Findings from these studies can consequently be applied to identify cortical sites of integration for distinct olfactory inputs and to dissect the relative contribution of genes and experience in olfactory neural circuit formation and function. These studies should have implications for understanding innate behaviors such as fear and mating and also facilitate the study of learning and memory.