Shared Resources - Tissue Procurement

项目总结(见说明)： 组织采购核心 容易接触到良性和恶性组织是癌症的宝贵来源 调查人员。组织采购核心旨在收集和存储高质量 来自各种来源的组织标本，并根据所提出的科学向HCCC调查人员提供这些标本。核心确保这些活动的开展符合涉及这类活动的所有规则和条例。中心及其工作人员与来自不同部门的临床医生合作，以： 1)确定并同意可能适合进行采集的患者。 2)与外科病理实验室的适当人员密切合作，确保充分的病人护理，同时最大限度地增加收集的标本数量 3)将有关标本的信息输入安全数据库并适当存储 4)执行严格的质量控制程序 5)将可用的组织分发给研究人员，以进行高质量的癌症研究 HCCC和爱荷华大学CTSA正在合作，进一步加强获得 生物群落。组织采购核心实施了CATISSUE，以加强组织采购的信息基础设施，并正在努力开发一种在向医疗中心登记时获得同意的方法，并将组织与已确定的临床数据联系起来，这将进一步提高组织对HCCC调查人员的效用。

PROJECT SUMMARY (See instructions): Tissue Procurement Core Ready access to both benign and malignant tissue is a valuable resource for cancer investigators. The Tissue Procurement Core is designed to collect and store high quality tissue specimens from a variety of sources and make these available to HCCC investigators based on the science proposed. The Core insures that these activities are performed in compliance with all rules and regulations covering such activity. The Core and its personnel work in cooperation with clinicians from various departments to: 1) Identify and consent patients from whom collection may be appropriate. 2) Work closely with appropriate individuals in the Surgical Pathology Laboratory to insure adequate patient care while maximizing the number of collected specimens 3) Enter information about specimens into a secure data base and store appropriately 4) Implement rigorous quality control procedures 5) Distribute available tissue to investigators for high quality cancer research The HCCC and University of lowa CTSA are collaborating to further strengthen access to biospecimens. The Tissue Procurement Core has implemented CaTISSUE to enhance the informatics infrastructure for Tissue Procurement, and is working to develop an approach to obtaining consent at the time of registration to the medical center, and link tissues with deidentified clinical data, that will further enhance the utility of tissue for HCCC investigators.