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中文摘要
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描述(由申请人提供):共济失调是一种致残和经常致命的神经系统疾病,由广泛的后天和遗传损伤引起。第四届共济失调研究者会议(AIM 2012)将汇集一份国际科学研究者名册,以解决共济失调的多学科性质,更好地定义共济失调的致病基础,并探索治疗这一基本无法治愈的疾病的途径。会议将集中讨论最新的科学进展和新兴的治疗转化方法,目的是实现以下五个目标:1)加强与共济失调研究相关的信息的开放交流; 2)促进全球研究人员之间的合作研究; 3)提高我们对人类共济失调疾病的理解; 4)加强对人类共济失调疾病的研究。4)建立共同调查和储存共济失调及其治疗相关数据的国际协议; 5)为初级研究人员提供展示其工作的机会, 该领域的更多成熟科学家,并有机会与患者和支持团体互动,使他们能够看到他们的工作的临床影响和重要性。AIM 2012将是促进共济失调研究和治疗方法合作和讨论的关键机制,这一点尤其重要,因为该领域正在进入美国和欧洲有意义的多中心临床试验阶段。AIM 2012会议的地点在德克萨斯州的圣安东尼奥,紧随着全国最大的共济失调基金会的年会,将最大限度地发挥这次会议对科学家和患者的影响。
英文摘要
DESCRIPTION (provided by applicant): Ataxia, a disabling and frequently fatal neurological disorder, is caused by a wide range of acquired and genetic insults. The Fourth Ataxia Investigators' Meeting, AIM2012, will assemble an international roster of scientific investigators to address the multi-disciplinary nature of ataxia, to define better the pathogenic basis of ataxia and to explore routes to therapy for what is largely an untreatable disease. The conference will focus on the most recent scientific advances and emerging translational approaches toward therapy, with the objective of achieving the following five goals: 1) Enhance the open exchange of information related to ataxia research; 2) Stimulate collaborative research between investigators worldwide; 3) Improve our understanding of human ataxic disorders; 4) Establish international protocols for the common investigation and storage of data related to ataxia and its treatment; 5) Provide junior investigators with an opportunity to present their work, interact with more established scientists in the field, and have an opportunity to interact with patients and support groups so that they can see the clinical impact and importance of their work. AIM2012 will represent a critical mechanism to facilitate collaboration and discussion on ataxia research and therapeutic approaches, which is of particularly great importance now that the field is entering the phase of meaningful, multi-center clinical trials both in the United States and Europe. The location of the AIM2012 meeting in San Antonio, Texas, dovetailing with the annual meeting of the largest ataxia foundation in the country, will maximize the impact of this meeting for both scientists and patients alike.
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Michigan Alzheimer's Disease Research Center
Core A: Administrative Core
Core A: Administrative Core
Michigan Alzheimer’s Disease Research Center-Supplement
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