CARRESS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 因急性失代偿性心力衰竭住院的患者，如果他们发生心肾综合征，定义为血清肌酸较基线增加≥ 0.3 mg/dl，同时表现出持续充血的体征和症状。该试验随机分为分级药物治疗组和超滤治疗组。 主要终点是96小时内体重和肌酐变化的双变量终点评估的变化。 该研究的目的是测试与阶梯式药物袢利尿护理相比，超滤是否会改善患者的肾功能并缓解充血 因急性失代偿性心力衰竭和心肾综合征住院。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Patients hospitalized with acute decompensated heart failure if they develop cardiorenal syndrome as defined by ain increase in serum creatine of or equal to .3 mg per deciliter from baseline while demonstrations signs and symptoms of persistent congestion. The trial is randomized to stepped pharmacologic care verses ultrafiltration. The primary endpoint is a change in the bivariate endpoint assessment of weight and change in creatinine within 96 hours. The goal of the study is to test whether ultrafiltration compared to stepped pharmacologic loop diuretic care will result in improved renal function and relief of congestion in patients hospitalized with acute decompensated heart failure and Cardio renal syndrome.