Histopathology Core

NEI的组织病理学核心致力于支持患者护理，视觉研究，以及NEI和NIH其他合作研究所的使命。这包括处理在手术中移除的人体组织（主要是眼部组织）和在尸检中收集的组织。该核心毛组织，切片和染色玻片的光和/或透射电子显微镜。组织病理学核心服务于临床分支和NEI校内研究计划下的所有NEI实验室，以及其他从事眼部和相关组织研究的NIH研究所。此外，核心还接受NIH（美国和国外）以外的临床医生和研究人员提交的临床和实验标本，以供咨询或合作。在2012财年，组织病理学中心接收并处理了大约5340个标本，产生了9336张染色玻片。此外，该实验室还对送去进行超微结构检测的病例材料进行了处理，产生了1683张电子显微镜图像。本财政年度还收到和处理了113个临床病例。患者标本共生成1139张组织学切片和94张电镜图像。有超过20份出版物包括了核心所做的工作。虽然我们大约95%的工作致力于NEI职责，但组织病理学核心也为NIH内外的研究项目提供服务。核心遵循美国国立卫生研究院内部研究项目的研究指导方针和美国国立卫生研究院制定的其他标准。

The Histopathology Core of the NEI is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. The Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which perform research involving ocular and related tissues. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for consultation or collaboration. During FY12, the Histopathology Core received and processed approximately 5340 specimens and yielded over 9336 slides stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 1683 electron microscopic images. This fiscal year, 113 clinical cases were also received and processed. The patient specimens produced 1139 histological slides and 94 electronic microscopic images. There are over 20 publications that include work performed by the Core. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.