Maintenance and Improvement of NINDS Infrastructure

以下实验室和研究支持领域在2012财年进行了重大改造： 为电路动力学和连接单元主任Kevin Briggman博士翻新电生理学和成像/显微镜实验室。地址：NIH Bethesda Campus，Bldg 35 为脑微循环科主任Afonso Silva博士改造动物成像和生理学实验室空间。地址：NIH Bethesda Campus，Bldg 49 为脑微循环科主任Wei Lu Silva博士翻新电生理学和细胞培养实验室。地址：NIH Bethesda Campus，Bldg 35 为神经系统感染科科长Avi Nath博士翻修化学实验室。地点，NIH Bethesda Campus，Bldg 10 为脑微循环科主任Afonso Silva博士翻修显微镜和基本实验室空间。地址：NIH Bethesda Campus，Bldg 49 为美国国立卫生研究院贝塞斯达校区10号楼外科神经病学分支主任Russ Lonser博士翻修基础实验室 波特神经科学研究中心第2期混合研究所实验楼的搬迁和启动活动，NINDS是牵头研究所。地址：NIH Bethesda Campus，Bldg 36 购买了以下主要共用设备，以支持大量的专业人员： - Carl Zeiss LSM 780 34通道光谱检测系统，带GaAsP外部探测器，用于功能和分子成像实验室的多光子和单光子成像 - 升级现有的Leica共聚焦显微镜，配备脉冲白光激光器和光成像设备的门控荧光检测功能 - 用于NINDS流式细胞术核心设施的10通道荧光显微镜成像系统 - Orbitrap Elite 10000带水再循环器，用于肽测序设施 - Porter神经科学研究中心二期服务器机房基础设施，混合研究所实验室大楼，NINDS是牵头研究所 - 功能和分子成像实验室17.6T磁体磁共振成像和光谱控制台

The following laboratories and research support areas underwent major renovations during FY 2012: Renovate Electrophysiology and imaging/microscopy laboratory for Dr. Kevin Briggman, Chief, Circuit Dynamics and Connectivity Unit. Location, NIH Bethesda Campus, Bldg 35 Renovate animal imaging and physiology laboratory space for Dr. Afonso Silva , Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 49 Renovate electrophysiology and cell culture laboratory for Dr. Wei Lu Silva, Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 35 Renovate chemistry laboratory for Dr. Avi Nath, Chief, Section of Infections of the Nervous Systems. Location, NIH Bethesda Campus, Bldg 10 Renovate microscopy and basic laboratory space for Dr. Afonso Silva , Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 49 Renovate basic laboratory for Dr. Russ Lonser, Chief, Surgical Neurology Branch, Location, NIH Bethesda Campus, Bldg 10 Relocation and activation activities for the Porter Neuroscience Research Center Phase 2, Mixed institute laboratory building, with NINDS has the lead institute. Location, NIH Bethesda Campus, Bldg 36 The following pieces of major shared equipment were purchased to support a large number of PIs: - Carl Zeiss LSM 780 34 Channel Spectral Detection system with GaAsP external detectors for Multi-photon and Single photon imaging for the Laboratory of Functional and Molecular Imaging - Upgrade existing Leica confocal microscope with pulsed white-light laser and capability for gated fluorescence detection for the Light Imaging Facility - 10-channel fluorescence microscope imaging system for the NINDS Flow Cytometry Core Facility - Orbitrap Elite 10000 with water recirculator for the Peptide Sequencing Facility - Infrastructure for server room for the Porter Neuroscience Research Center Phase 2, a mixed institute laboratory building, with NINDS has the lead institute - A Magnetic Resonance Imaging and Spectroscopy Console for a 17.6T Magnet for The Laboratory of Functional and Molecular Imaging