Statistical/Data Base Core

在与计划项目主任近20年的密切合作基础上， 该计划的许多调查人员、合作者和顾问，该核心的主要领导者， 其职责将是保证在开展活动时采用良好的统计和科学做法， 每一个研究方案;在研究的设计和开发中与研究人员合作 协议;确保为项目制定的统计分析计划的实施; 开发新的分析方法，并调整和采用文献中出现的新方法 与特定目标相关的;确保研究的公平，准确和公正的出版 调查结果;并监督核心工作人员的管理。具体目标和职能是： 具体目标（职能） 核心E的具体目标（职能）是： 满足三个项目的特定生物统计需求，包括提供创新解决方案， 这些项目带来的数据分析挑战; 为所有项目中的人体方案提供临床数据库管理基础设施支持;以及 为所有项目的中央统计方案编制提供资源 在每项研究方案的实施中普遍促进良好的统计和科学实践， 开发新的分析方法，并调整和采用文献中出现的新方法 与具体目标相关的，并确保公平，准确和公正的出版物 研究结果。

Building on nearly 20 years of close collaboration with the Program Project Director and nearly as long with many of the Program's investigators, collaborators, and consultants, Leader of this Core's primary responsibilities will be to guarantee the application of good statistical and scientific practice in the conduct of every research protocol; to collaborate with investigators in the design and development of research protocols; to insure the implementation of the statistical analysis plans developed for the Projects; to develop new approaches to analysis and to adapt and adopt new approaches appearing in the literature that are relevant to the Specific Aims; to insure the fair, accurate, and unbiased publication of research findings; and to provide oversight in the management of Core staff. Specific Aims and Functions are: SPECIFIC AIMS (FUNCTION) The Specific Aims (functions) of Core E are: To meet the specific biostatistical needs of the three Projects including providing innovative solutions to data analysis challenges arising from these projects; To support clinical database management infrastructure for the human protocols in all projects; and To provide a resource for centralized statistical programming for all projects To generally promote good statistical and scientific practice in the conduct of every research protocol, to develop new approaches to analysis and to adapt and adopt new approaches appearing in the literature that are relevant to the Specific Aims, and to insure the fair, accurate, and unbiased publication of research findings.