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中文摘要
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前列腺癌计划由来自多个学科的24名基础和临床科学家组成,其中包括9个部门合作,将研究转化为流行病学、预防、分期方面的进展 以及前列腺癌的治疗。项目教师代表4个研究生项目的成员:PIBS, 生物工程和化学生物学。前列腺癌计划的目标是促进 跨学科研究,从与癌症发生、早期发现和疾病进展相关的生物和环境因素出发,更好地了解前列腺癌的生物学 来预测疾病进展的生物学基础。最终的目标是发展 新的干预策略将改善被诊断为前列腺癌或有患前列腺癌风险的男性的生活。前列腺癌计划通过以下途径追求这些目标 正在进行的五个主要专题领域的工作:(1)前列腺癌流行病学;(2)成像和风险 评估策略;(3)癌症进展的遗传学和生物学;(4)结果研究,健康 资源利用和医疗决策;以及(5)新的治疗目标和方法。这个 该计划在上一个预算年度总共有7,248,631美元的同行评审支持。该计划有26%的计划内 方案间出版物占23%。
英文摘要
The Prostate Cancer Program comprises 24 basic and clinical scientists from several disciplines, including 9 Departments working together to translate research into advances in the epidemiology, prevention, staging and treatment of prostate cancer. Program faculty represent membership in 4 graduate programs: PIBS, BMS, Bioengineering, and Chemical Biology. The goals of the Prostate Cancer program are to promote interdisciplinary research that will allow a better understanding of the biology of prostate cancer, from the biologic and environmental factors associated with carcinogenesis, early detection and disease progression to prognostication and the biologic basis of disease progression. The ultimate goal is the development of novel intervention strategies that will improve the lives of men who carry a diagnosis of prostate cancer or who are at risk of developing prostate cancer. The Prostate Cancer Program pursues these goals through ongoing work in five major thematic areas: (1) Prostate Cancer Epidemiology; (2) Imaging and Risk Assessment Strategies; (3) Genetics and Biology of Cancer Progression; (4) Outcomes Research, Health Resource Utilization and Medical Decision Making; and (5) Novel Therapeutic Targets and Approaches. The Program has $7,248,631 Total peer reviewed support for the last budget year. The Program has 26% intraprogrammatic and 23% inter-programmatic publications.
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Predictive Markers in Metastatic Renal Cancer
PROSTATE CANCER PROGRAM
04557: A PHASE I/II STUDY OF DOCETAXEL/PREDNISONE AND PTK 787/ZK 222584 IN PR
EFFECTS OF BICALUTAMIDE MONOTHERAPY ON BONE DENSITY IN PROSTATE CANCER
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