Effect Of Diet and Other Early Exposures on Child Health and Development

饮食和其他早期暴露可能会影响儿童发育和几种慢性疾病的风险，但需要进行更多的研究。 在这个包罗万象的项目中描述的当前研究包括一个项目，如下所述。 胎盘的重量经常被测量，可以反映胎儿在妊娠期间暴露于某些激素的水平。 在我们今年发表的关于这一主题的报告中，我们表明胎盘重量是怀孕期间雌激素暴露的一个有用指标，这一观察结果将用于研究成年后慢性疾病的早期风险因素。 我们还开始了一个项目，根据雅芳父母和儿童纵向研究的数据，研究怀孕期间的身体活动与后代神经发育的关系。 根据动物实验的结果可以预测，如果母亲在怀孕期间锻炼，儿童的早期语言发育会得到改善，而不受测量的混杂因素的影响。草稿是一种准备工作. 去年进展： 发表了1篇论文（见下文）。

Diet and other early exposures may affect child development and the risk of several chronic diseases, but additional research is needed. The current research described in this catch-all project comprises one project, described below. The weight of the placenta is often measured and may reflect the level of exposure of the fetus to certain hormones during gestation. In the report we published this year on this topic, we showed that placental weight was a useful indicator of estrogen exposure during pregnancy, an observation that will be of use in studies examining early-life risk factors for chronic diseases in adulthood. We also began work on a project examining physical activity during pregnancy in relation to neurodevelopment in offspring, based on data from the Avon Longitudinal Study of Parents and Children. As would be predicted on the basis of results in animal experiments, if the mother excercised during pregnancy the children's early language development was improved, independently of measured confounding factors. A draft manuscript is is preparation. Last years progress: 1 paper was published (see list below).