Histopathology Core

NEI的组织学核心致力于支持患者护理，视力研究以及NEI和NIH其他合作机构的使命。这包括处理在手术中取出并在尸检中收集的人体组织（主要是眼部组织）。Core对组织、切片和染色载玻片进行大体检查，以进行光学和/或透射电子显微镜检查。在NEI内，组织学核心服务于临床分支和NEI校内研究计划下的所有NEI实验室，以及其他NIH研究所，这些研究所进行涉及眼部和相关组织的研究。此外，该中心还接收NIH以外（美国和国外）的临床医生和研究人员提交的临床和实验标本进行咨询。在FY 11期间，从超过7780份标本中制备了大约3994个组织块，并切割和染色了超过9534个载玻片。此外，该实验室还处理了送来的病例材料进行超微结构检查，从1893个厚切片和314个样本中获得了2004张电子显微镜图像。本财政年度还收到并处理了757份咨询标本，包括截至2011年8月14日的118例临床病例。虽然我们95%的工作是致力于NEI的职责，但组织学核心也为NIH内外的研究项目提供服务。核心遵循NIH内部研究计划的研究指导方针和NIH制定的其他标准。

The Histopathology Core of the NEI is devoted to supporting the patient care, vision research, and mission of the NEI and other collaborative institutes at the NIH. This consists of processing human tissues (mainly ocular tissues) that were removed in surgeries and collected at autopsies. The Core grosses the tissues, sections and stains slides for light and/or transmission electron microscopy. Within the NEI, the Histopathology Core serves the Clinical Branch and all NEI laboratories under the NEI Intramural Research Program, as well as other NIH institutes, which perform research involving ocular and related tissues. In addition, the Core receives clinical and experimental specimens submitted by clinicians and investigators outside NIH (USA and abroad) for consultation. During FY11, approximately 3994 tissue blocks were prepared from over 7780 specimens and over 9534 slides were cut and stained. Additionally, the laboratory processed case materials sent for ultrastructure, which produced 2004 electron microscopic images from 1893 thick sections and 314 samples. This fiscal year, 757 consultation specimens including 118 clinical cases as of August 14, 2011 were also received and processed. Although about 95% of our effort is devoted to NEI duties, the Histopathology Core also performs services for research projects inside and outside the NIH. The core follows the guidelines for the conduct of research in the intramural research program at the NIH and other standards set by the NIH.