COBRE: LOUISVILLE RES FOUND INC: CORE E: BIOPHYSICAL FACILITY

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 生物物理核心设施位于布朗癌症中心的四楼，位于一个新装修的504平方英尺的实验室里。这一最先进的设备提供了执行热量测量、电子光谱、快速动力学和流体动力学测定的能力。专业知识由主任J.布拉德·查里斯博士和设施经理尼古拉·加贝特博士提供，他们两人在这一领域都有相当丰富的经验。除了仪器设备外，该设施还提供生物物理方法和数据分析方面的培训，并与布朗癌症中心的分子建模和结构生物学核心相结合，以加强药物发现工作。生物物理学核心设施为所有MT-Cobre研究人员提供了独特的资源。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Biophysics Core Facility is located on the fourth floor of the Brown Cancer Center in a newly renovated 504 square-foot laboratory. This state-of-the-art facility provides the capability to perform calorimetry, electronic spectroscopy, rapid kinetics and hydrodynamics determinations. Expertise is provided by the director, Dr. J. Brad Chaires, and by Dr. Nichola Garbett, the facility manager, both of whom have considerable experience in this area. In addition to the instrumentation, this facility provides training in biophysical methods and data analysis and is integrated with the molecular modeling and structural biology cores at the Brown Cancer Center to enhance drug discovery efforts. The Biophysics Core Facility provides a unique resource to all MT-COBRE investigators.