UNDERGRADUATE AND MEDICAL STUDENT RESEARCH PROJECTS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 在资源主任和工作人员的指导下，学生参加了波士顿大学本科生研究机会计划和2010-2011学年医学生研究计划下的MS资源研究。波士顿大学化学系学生在年度本科生研究研讨会上介绍他们的工作。来自其他机构的本科生也有资格在资源进行研究。 先生化学专业的Nikhil Madhusudhan于2007年秋季加入了该资源。他选择参加BU是基于在资源/CPC进行研究的机会。他从事的项目涉及电泳蛋白质分离，作为我们的蛋白质森林设备β测试的一部分，并使用该设备在他的淀粉样蛋白转甲状腺素蛋白的氧化翻译后修饰的研究。2011年5月毕业后，他计划上医学院。 先生Paul Romesser在资源合作者Gerald Denis的指导下工作了几年。他密切参与了Brd 2复合物的蛋白质组学研究。他在2005年由Costello教授和Mann教授组织的Keystone会议和2007年ASMS会议上展示了他的研究海报。2006年夏天，Romesser先生获得了特别资助，使他能够在资源和CPC全职工作。Romesser先生于2006年秋季开始在BUSM进行医学研究，但继续在Resource进行研究。去年发表了一篇描述他的研究结果的手稿。他中断了医学研究，在霍华德休斯基金会的一个项目下，在NIH进行了两年的研究。他将于2011年5月以优异成绩毕业于波士顿大学医学院。 教授Zaia在该项目中聘请了一组计算机科学专业的本科生来开发支持聚糖分析的软件。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Guided by the Resource Directors and staff, students participated in MS Resource research under the Boston University Undergraduate Research Opportunities Program and programs for medical student research in the 2010-2011 academic year. Boston University Chemistry Dept. students make presentations on their work at the annual Undergraduate Research Symposium. Undergraduates from other institutions are also eligible to conduct research at the Resource. Mr. Nikhil Madhusudhan, a chemistry major, joined the Resource in fall 2007. His choice to attend BU was strongly based on the opportunity to perform researdh at the Resource/CPC. He worked on projects that involve electrophoretic protein separation as part of our beta-test of the Protein Forest device and used this device in his investigation of oxidative post-translational modifications of the amyloid protein transthyretin. After his graduation in May 2011, he plans to attend medical school. Mr. Paul Romesser worked under the direction of Resource collaborator Gerald Denis for several years. He was closely involved in proteomics studies of Brd2 complexes. He presented poster on his research at the 2005 Keystone Conference organized by Prof. Costello and Prof. Mann and at the 2007 ASMS meeting. For the summer of 2006, Mr. Romesser received special funding to allow him to work full time at the Resource and CPC. Mr. Romesser began his medical studies at BUSM in Fall 2006 but continued to carry out research at the Resource. A manuscript describing his results was published last year. He interrupted his medical studies to perform two years of research at NIH, under a Howard Hughes Foundation program. He will graduate from BU School of Medicine summa cum laude in May 2011. Prof. Zaia has engaged a group of undergraduate students in the Computer Science program in the project to develop software to support glycan analysis.