HIGH FIELD MRI: LIMITATIONS AND SOLUTIONS

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 Drs. Chris柯林斯、Qing Yang、Vaughan、Garwood、Ugurbil和各自的工作人员正在合作，以确定和描述局限性，并发现和开发7 T及更高温度下人体MRI的新解决方案。柯林斯博士和杨博士（原迈克尔·史密斯博士）的宾夕法尼亚州立大学好时医学中心实验室率先开发了高保真度、高度分段的人体解剖模型，用于SNR、SAR、B1均匀性和其他物理参数的数值模拟。 通过理论模拟和经验验证，我们能够探索问题，并找到新的解决方案，在前所未有的场强人体成像。 这项工作部分得到了明尼苏达州与宾夕法尼亚州立大学的NIH-PAR-02-010的分包合同的支持，并得到了宾夕法尼亚州立大学与沃恩的NIH-EB 000895的合作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Drs. Chris Collins, Qing Yang, Vaughan, Garwood, Ugurbil, and respective staffs are collaborating to identify and characterize the limitations, and to discover and develop new solution for MRI of humans at 7T and higher. The Penn State Hershey Medical Center Lab of Drs. Collins and Yang (formerly that of Dr. Michael Smith), has pioneered the development of high fidelity, highly segmented human anatomic models for numerical simulations of SNR, SAR, B1 uniformity and other physical parameters. Through theoretical simulation and empirical validation, we are able to explore the problems and find new solutions to human imaging at unprecedented field strengths. This work is supported in part by a Minnesota sub-contract to Penn State's NIH-PAR-02-010, and by Penn State's subcontract with Vaughan's NIH-EB000895.