TMRNA MEDIATED TAGGING AND PROTEIN DEGRADATION
TMRNA MEDIATED TAGGING AND PROTEIN DEGRADATION
批准号:
8361644
负责人:
Robert T Sauer
金额:
$0.11万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-04-01 至 2012-03-31
关键词:
Adaptor Signaling ProteinFundingGrantMediatingMolecularNational Center for Research ResourcesPeptide HydrolasesPrincipal InvestigatorResearchResearch InfrastructureResourcesSignal TransductionSourceUnited States National Institutes of Healthcostprotein aminoacid sequenceprotein degradationstructural biology
中文摘要
这个子项目是利用资源的许多研究子项目之一。
由NIH/NCRR资助的中心拨款提供。对子项目的主要支持
子项目的首席调查员可能是由其他来源提供的,
包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能
表示该子项目使用的中心基础设施的估计数量,
不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。
我们正在确定多肽序列和接头蛋白针对细菌蛋白酶降解蛋白质的机制,并阐明调节变构PDZ-蛋白酶的分子信号和机制。
英文摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
We are determining mechanisms by which peptide sequences and adaptor proteins target proteins for degradation by bacterial proteases and elucidating the molecular signals and mechanisms that regulate allosteric PDZ-proteases.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Structure and function of ClpXP
-
批准号:10198307
-
项目类别:
-
资助金额:$38.57万
-
财政年份:2021
-
负责人:Robert T Sauer
-
依托单位:
Structure and function of ClpXP
-
批准号:10589839
-
项目类别:
-
资助金额:$38.78万
-
财政年份:2021
-
负责人:Robert T Sauer
-
依托单位:
Structure and function of ClpXP
-
批准号:10373109
-
项目类别:
-
资助金额:$38.78万
-
财政年份:2021
-
负责人:Robert T Sauer
-
依托单位:
SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION
-
批准号:8361605
-
项目类别:
-
资助金额:$0.11万
-
财政年份:2011
-
负责人:Robert T Sauer
-
依托单位:
SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION
-
批准号:8169212
-
项目类别:
-
资助金额:$0.52万
-
财政年份:2010
-
负责人:Robert T Sauer
-
依托单位:
TMRNA MEDIATED TAGGING AND PROTEIN DEGRADATION
-
批准号:8169268
-
项目类别:
-
资助金额:$0.52万
-
财政年份:2010
-
负责人:Robert T Sauer
-
依托单位:
SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION
-
批准号:7955082
-
项目类别:
-
资助金额:$0.25万
-
财政年份:2009
-
负责人:Robert T Sauer
-
依托单位:
TMRNA MEDIATED TAGGING AND PROTEIN DEGRADATION
-
批准号:7955198
-
项目类别:
-
资助金额:$0.25万
-
财政年份:2009
-
负责人:Robert T Sauer
-
依托单位:
DESIGN OF SSPB VARIANTS FOR PROBING SSPB FUNCTION
-
批准号:7721200
-
项目类别:
-
资助金额:$0.7万
-
财政年份:2008
-
负责人:Robert T Sauer
-
依托单位:
PROTEIN RE-DESIGN BY NONCYCLIC REARRANGEMENT OF PROTEIN SECONDARY STRUCTURE
-
批准号:7182930
-
项目类别:
-
资助金额:$1.02万
-
财政年份:2005
-
负责人:Robert T Sauer
-
依托单位:
DESIGN OF SSPB VARIANTS FOR PROBING SSPB FUNCTION
-
批准号:7369491
-
项目类别:
-
资助金额:$0.13万
-
财政年份:2005
-
负责人:Robert T Sauer
-
依托单位:
DESIGN OF SSPB VARIANTS FOR PROBING SSPB FUNCTION
-
批准号:7182915
-
项目类别:
-
资助金额:$1.02万
-
财政年份:2005
-
负责人:Robert T Sauer
-
依托单位:
PROTEIN DESIGN TOPOLOGY
-
批准号:6972754
-
项目类别:
-
资助金额:$2.1万
-
财政年份:2004
-
负责人:Robert T Sauer
-
依托单位:
REPRESSOR AND ANTIREPRESSOR PROTEINS OF BACTERIOPHAGES
-
批准号:2060426
-
项目类别:
-
资助金额:$32.43万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
REPRESSOR AND ANTIREPRESSOR PROTEINS OF BACTERIOPHAGE
-
批准号:3126890
-
项目类别:
-
资助金额:$30.69万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
REPRESSOR AND ANTIREPRESSOR PROTEINS OF BACTERIOPHAGE
-
批准号:6510104
-
项目类别:
-
资助金额:$46.55万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
REPRESSOR AND ANTIREPRESSOR PROTEINS OF BACTERIOPHAGE
-
批准号:2614876
-
项目类别:
-
资助金额:$41.39万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
Bacterial protein tagging, degradation & ribosome rescue
-
批准号:6728294
-
项目类别:
-
资助金额:$56.25万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
Bacterial protein tagging, degradation & ribosome rescue
-
批准号:7217984
-
项目类别:
-
资助金额:$64.48万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
Bacterial Protein Tagging, Degradation and Ribosome Rescue
-
批准号:7464328
-
项目类别:
-
资助金额:$68.82万
-
财政年份:1980
-
负责人:Robert T Sauer
-
依托单位:
海外基金