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PROTEOMICS AND COMPARATIVE GENOMIC INVESTIGATIONS REVEAL HETEROGENEITY IN EVOLUT

PROTEOMICS AND COMPARATIVE GENOMIC INVESTIGATIONS REVEAL HETEROGENEITY IN EVOLUT
蛋白质组学和比较基因组研究揭示了进化的异质性
批准号:
8365865
负责人:
WILLIE J SWANSON
金额:
$0.65万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2011
资助国家:
美国
项目状态:
已结题
起止时间:
2011-09-01 至 2012-06-30

项目摘要

项目成果

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中文摘要
翻译
这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的, 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量, 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 男性生殖健康受到精液的强烈影响。除了与雌性环境相互作用外,精液还介导精子的重要生理特征,包括获能和运动。在哺乳动物中,雄性生殖道显示出惊人的区域化程度,至少有六种不同的组织类型提供与精液中精子结合的物质。虽然在某些物种中已经进行了整个射精的研究,但我们缺乏对不同附属组织产生的特定蛋白质的全面了解。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization, with at least six distinct tissue types contributing material that is combined with sperm in an ejaculate. While studies of whole ejaculates have been undertaken in some species, we lack a comprehensive picture of the specific proteins produced by different accessory tissues.
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An evolutionary and proteomic search for human gamete recognition proteins that mediate zona pellucida dissolution
  • 批准号:
    10370974
  • 项目类别:
  • 资助金额:
    $22.93万
  • 财政年份:
    2021
  • 负责人:
    WILLIE J SWANSON
  • 依托单位:
An evolutionary and proteomic search for human gamete recognition proteins that mediate zona pellucida dissolution
  • 批准号:
    10493286
  • 项目类别:
  • 资助金额:
    $19.04万
  • 财政年份:
    2021
  • 负责人:
    WILLIE J SWANSON
  • 依托单位:
Detailed functional analysis of gamete recognition protein interactions
  • 批准号:
    9086388
  • 项目类别:
  • 资助金额:
    $37.65万
  • 财政年份:
    2014
  • 负责人:
    WILLIE J SWANSON
  • 依托单位:
Detailed functional analysis of gamete recognition protein interactions
  • 批准号:
    8877577
  • 项目类别:
  • 资助金额:
    $37.08万
  • 财政年份:
    2014
  • 负责人:
    WILLIE J SWANSON
  • 依托单位:
国内基金
海外基金
Journal of Integrative Plant Biology
  • 批准号:
    31024801
  • 项目类别:
    专项基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2010
  • 负责人:
    贺萍
  • 依托单位: