International Copper Meeting: Copper in Biology

描述(申请人提供)：2012年生物铜会议将于2012年9月30日至10月3日在意大利阿尔盖洛举行。这将是本系列会议的第八次会议。铜线输入 生物学已经成为各种研究人员的旗舰会议，他们专注于生物和健康中的环境铜。这是同类会议中唯一一次特别 专注于铜。铜是几乎所有生命形式的一种微量必需营养素，但这一点是相同的 金属具有潜在的毒性。因此，生物体进化出了专门的动态平衡机制，确保从环境中充分吸收痕量铜，同时将铜化学的毒副作用降至最低。铜对人类健康的影响早已为人所知，但现在，随着监测铜动态的尖端工具和铜代谢缺陷的新模型系统的出现，研究人员开始认识到铜对多个器官系统的广泛影响以及铜相关疾病的机制。铜12会议旨在将从基础生物无机化学家到细胞生物学家和遗传学家再到翻译科学家的各种科学家聚集在一起，传播新的未发表的信息，建立合作关系，并促进新的研究方向。特别是，年轻的初级调查人员将在整个会议期间以及任何代表不足的少数族裔与会者中露面。 与公共卫生的相关性：第8届生物铜会议(铜12)旨在促进对环境铜在基础生物学以及健康和疾病中的影响的了解。环境中的铜不仅是生命所必需的，而且具有潜在的毒性和 与特定的疾病状态有关。致力于了解铜在生物学中的复杂性的研究小组多种多样，从基础化学家、生物学家到内科医生。通过生物铜会议，这些不同的研究人员有机会面对面地互动，从而分享研究方面的新突破，并发展合作，推动该领域的发展。

DESCRIPTION (provided by applicant): The 2012 meeting of Copper in Biology will take place in Alghero, Italy Sept 30-Oct 3, 2012. This will be the 8th meeting of this series. Copper in Biology has become the flagship conference for diverse investigators that focus on environmental copper in biology and health. It is the only conference of its kind that specifically focuses on copper. Copper is a trace essential nutrient for virtually all life forms, but this same metal is potentially toxic. As such, organisms have evolved with specialized homeostatic mechanisms that ensure adequate uptake of trace copper from the environment whilst minimizing the toxic side reactions of copper chemistry. The impact of copper on human health has long been known, but now with cutting edge tools for monitoring copper dynamics and new model systems for copper metabolism defects, investigators are beginning to appreciate the extensive impact of copper on multiple organ systems and the mechanisms that underlie copper related disorders. The Copper 12 meeting aims to bring together a diversity of scientists ranging from basic bioinorganic chemists to cell biologists and geneticists to translational scientists to disseminate new unpublished information, to establish collaborations and foster new directions for research. In particular, young junior investigators will be show-cased throughout the conference as well as any under-represented minority participants. PUBLIC HEALTH RELEVANCE: The 8th meeting of Copper in Biology (Copper 12) seeks to advance understanding of the impact of environmental copper in basic biology and in health and disease. Copper in the environment is not only essential for life, but is potentially toxic and has been associated with specific disease states. The group of researchers devoted to understanding the complexity of copper in biology is diverse and extend from basic chemists and biologists to physicians. Through the Copper in Biology conference, such diverse investigators have an opportunity to interact face-to-face and thereby share new breakthroughs in research and develop collaborations to advance the field.