Informatics

信息学核心构成了寻求技术援助的项目调查人员的资源 在研究的各个阶段支持数据管理、统计分析和分析解释 过程中心调查人员收集的数据来自广泛的来源，包括对以下方面的研究： 啮齿类动物（P2、P4、P5、P6）灵长类动物（P2、P3）和人类（P1、P2），以及各种方法 包括电生理学（P3，P4，P5，P6），动物行为学（P3，P4），神经解剖学（P2，P3，P4，P5，P6）和 人类行为和成像研究（PI）。所有的项目PI都是资深的，有声望的调查员， 在自己感兴趣的领域有数据收集和分析的经验。数据的种类和数量 代表了中心的巨大潜力，但也强调了数据协调的重要性， 整合和共享，以实现中心的目标。该核心的主要重点是协助 及时整合和传播跨项目的数据，以提高中心的总体目标。有 核心C的四大使命首先是确保个人数据的一致性和质量 项目调查员可以随时查阅这些资料。的 核心的第二个使命是为下列统计设计和分析提供密集的协调投入： 中心研究从研究开始到结果的出版和传播。第三次使命 核心C将开发跨物种的内侧和眶皮层及其 内囊/纹状体中的突起。这些模型将分别基于三维模型 在P2和核心B中开发，以及P1中的PET研究。核心的第四个使命是开发时间 系列分析将有助于解释项目3和4中收集的电生理数据 与高频VCA/S刺激对局部场电位、振荡状态和 皮层中单个神经元的群体编码。 相关性（参见说明）： 项目之间的数据协调和共享在这个跨越多个地点和不同 方法论。该核心将管理一个集中的数据存储库，并提供统计和 为中心的各个项目提供计算支持。

The Informatics core constitutes a resource for project investigators seeking assistance with technical support for data management, statistical analyses, and analytic interpretation at all stages of the research process. The data collected by Center investigators comes from a wide range of sources including studies of rodents(P2,P4,P5,P6) primates(P2,P3), and humans(P1,P2), as well as across diverse methodologies including electrophysiologic(P3,P4,P5,P6), animal behavior(P3,P4), neuroanatomic (P2,P3,P4,P5,P6) and human behavior and imaging studies(PI). All of the project Pis are senior, well-established investigators who are experienced in data collection and analysis in their own fields of interest. The variety and volume of data represent enormous potential for the Center but also underscore the importance of data coordination, integration, and sharing to achieve the Center's aims. The primary focus of this core will be to assist in the timely integration and dissemination of this data across projects to enhance overall Center goals. There are four main missions of Core C. The first is to ensure the uniformity and quality of data across the individual projects and to collect them in a central repository that is readily accessible to project investigators. The second mission of the core is to provide intensive coordinated input into the statistical design and analysis of Center studies from study inception through publication and dissemination of results. The third mission of Core C will be to develop computational models across species of medial and orbital cortex and their projections in the internal capsule/striatum. These models will be based respectively on the 3-D models developed in P2 and Core B, and on the PET studies in P1. The fourth mission of the core is to develop time series analyses that will assist in the interpretation of electrophysiological data collected in projects 3 and 4 related to the effects of high frequency VCA/S stimulation on local field potentials, oscillatory states and population coding of individual neurons in cortex. RELEVANCE (See instructions): Data coordination and sharing between projects is critical in this Center that spans multiple sites and diverse methodologies. This Core will manage a centralized data repository as well as provide the statistical and computational support for the individual projects in the Center.