Improving pain and movement outcomes in symptomatic knee osteoarthritis

人们比其他任何疾病都更害怕患上疼痛的膝骨性关节炎(OA)--它被认为是进行性的和不可治愈的。它经常阻止人们移动和保持健康，给患者和医疗保健系统带来巨大负担。这项研究计划旨在了解大脑和神经系统的哪些过程可能是这些疼痛和运动问题的基础，以及新的脑靶向治疗是否有帮助。这将使我们能够更好地将治疗与患者的需求相匹配。

People fear getting painful knee osteoarthritis (OA) more than any other disease – it is seen as progressive and incurable. It often stops people from moving and staying healthy, resulting in an enormous burden on sufferers and the health care system. This program of research aims to understand what brain & nervous system processes might underlie these pain and movement problems and whether new brain-targeting treatment helps. This will allow us to better match treatment to what patients need.