Maintenance and Improvement of NINDS Infrastructure

国立卫生研究院 NINDS设施规划/设备 35号楼，GF352 - 4 以下实验室和研究支持领域在2013财年进行了翻新： 1. 为电路动力学和连接单元主任Kevin Briggman博士翻新电生理学和成像/显微镜。地点，NIH校园，35号楼。 2. 为脑微循环科主任阿方索席尔瓦博士改造动物成像和生理学实验室空间。地点：NIH Bethesda Campus，Bldg 35。 3. 为美国国立卫生研究院贝塞斯达校区10号楼外科神经病学分支主任Russ Lonser博士翻修显微镜和基础实验室。 4. 波特神经科学研究中心第2阶段的搬迁和激活活动，混合研究所实验室大楼，NINDS作为牵头研究所。地点：NIH Bethesda Campus，Bldg 36。 5. 翻修神经细胞骨架蛋白调节科科长Harish Pant博士的办公室。地点，NIH校园，49号楼。 6. 与NINDS兽医人员一起搬迁和翻新与外科神经学分支相关的动物手术室。地点：NIH Bethesda Campus，Bldg 49。 7. 为电路动力学和连接部主任Kevin Briggman博士执行引擎盖升级和相关实验室改造。地点，NIH校园，37号楼。 8. 为袁泉博士（枝晶形态发生和塑性研究室主任）进行实验室装修。 地点：NIH Bethesda Campus，Bldg 35。 9. 为分子生理学和生物物理学科科长Dr.Swartz翻修内窥镜室。地点：NIH Bethesda Campus，Bldg 35。 10. 为NINDS/NIMH仪器科科长乔治Dold翻修办公室。地点：NIH Bethesda Campus，Bldg 13。 11. 为Abhik Ray-Chaudhury博士翻修和搬迁办公室。 地点：NIH Bethesda Campus，Bldg 10。 12. 为临床主任办公室主任Avi Nath博士翻修临床中心待命室。地点：NIH Bethesda Campus，Bldg 10。 13. F-Wing项目的搬迁和激活活动，混合研究所实验室翼。实验室建设包括三个PI的实验室和办公室工作，Dragan Maric博士，FACS设施负责人，Gene Major博士，分子医学和病毒学科科长，以及Dorian McGavern博士，病毒免疫学和活体成像科科长。地点：NIH Bethesda Campus，Bldg 10。 购买了以下主要共用设备，以支持大量的专业人员： 1. 将现有Thermo Orbitrap Velos质谱仪升级为临床蛋白质组学单元的Thermo Orbitrap Elite等效质谱仪 2. Shimadzu Percent工作站用于临床蛋白质组学部门 3. 用于蛋白质/肽测序设备的Microlab液体分析仪 4. 自动化TALEN用于国家关节炎、肌肉骨骼和皮肤疾病研究所（NIAMS）和国家神经疾病和中风研究所（NINDS）之间的合作项目 5. 11.7T超导磁体系统用于功能和分子成像实验室的动物MRI 6. 用于人脑成像的3T MRI系统是国家酒精滥用和酒精中毒研究所（NIAAA）、国家儿童健康和人类发展研究所（NICHD）、国家药物滥用研究所（NIDA）、国家心理健康研究所（NIMH）和国家神经疾病和中风研究所（NINDS）之间共同倡议的一部分 7. 功能和分子成像实验室超高动物MRI的集成梯度动物成像

NATIONAL INSTITUTES OF HEALTH NINDS Facilities Planning / Equipment Bldg 35, GF352-4 The following laboratories and research support areas underwent renovations during FY 2013: 1. Renovate Electrophysiology and imaging/ microscopy for Dr Kevin Briggman, Chief, Circuit Dynamics and Connectivity unit. Location, NIH Campus, Bldg 35. 2. Renovate animal imaging and physiology laboratory space for Dr Alfonso Silva, Chief, Cerebral Microcirculation Unit. Location, NIH Bethesda Campus, Bldg 35. 3. Renovate microscopy and basic laboratory for Dr Russ Lonser, Chief, Surgical Neurology Branch, Location, NIH Bethesda Campus, Building 10. 4. Relocation and activation activities for the Porter Neuroscience Research Center Phase 2, Mixed institute laboratory building, with NINDS as the lead institute. Location, NIH Bethesda Campus, Bldg 36. 5. Renovate the office of Dr Harish Pant, Chief, Neuronal Cytoskeletal Protein Regulation Section. Location, NIH Campus, Bldg 49. 6. Relocate and renovate an Animal Procedure Room Associated with the Surgical Neurology Branch in conjunction with the NINDS Veterinary Staff. Location, NIH Bethesda Campus, Bldg 49. 7. Perform Hood upgrade and associated laboratory renovation for Dr Kevin Briggman, Chief, Circuit Dynamics and Connectivity unit. Location, NIH Campus, Bldg 37. 8. Perform a lab renovation and fit-out for Dr Quan Yuan, Chief, Dendrite Morphogenesis and Plasticity Unit. Location, NIH Bethesda Campus, Bldg 35. 9. Renovate Scope Room for Dr Kenton Swartz, Chief, Molecular Physiology & Biophysics Section. Location, NIH Bethesda Campus, Bldg 35. 10. Renovate offices for the NINDS/ NIMH Section on Instrumentation for George Dold, Chief, Section on Instrumentation (NIMH). Location, NIH Bethesda Campus, Bldg 13. 11. Renovate and Relocate the Office for Dr Abhik Ray-Chaudhury. Location, NIH Bethesda Campus, Bldg 10. 12. Renovate the Clinical Center On-Call Room for Dr Avi Nath, Director, Office of the Clinical Director. Location, NIH Bethesda Campus, Bldg 10. 13. Relocation and activation activities for the F-Wing project, Mixed institute laboratory wing. Laboratory construction includes work for laboratories and offices for three PIs, Dr Dragan Maric Chief, FACS Facility, Dr Gene Major, Chief, Molecular Medicine & Virology Section, and Dr Dorian McGavern, Chief, Viral Immunology and Intravital Imaging Section. Location, NIH Bethesda Campus, Bldg 10. The following pieces of major shared equipment were purchased to support a large number of PIs: 1. Upgrade existing Thermo Orbitrap Velos mass spectrometer to Thermo Orbitrap Elite equivalent for the Clinical Proteomics Unit 2. Shimadzu Perfinity Workstation for the Clinical Proteomics Unit 3. Microlab Liquid Handler for the Protein/Peptide Sequencing Facility 4. Automated TALEN for a collaborative project between the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Institute of Neurological Disorders and Stroke (NINDS) 5. 11.7T Superconducting Magnet system for MRI of animals for the Laboratory of Functional and Molecular Imaging 6. 3T MRI System for human brain imaging as part of a shared initiative between the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Child Health and Human Development (NICHD), National Institute on Drug Abuse (NIDA), National Institute of Mental Health (NIMH), and National Institute of Neurological Disorders and Stroke (NINDS) 7. Animal imaging gradient with integrated shims for ultra-high animal MRI for the Laboratory of Functional and Molecular Imaging