Integrated Physiology Training: Molecule to Organism

描述（由申请人提供）：在过去的二十年里，全国各地的生理学部门的培训经历了一个转变，使学生无法彻底理解从整个动物到细胞和分子水平的学科广度。一个例外是威斯康星州（MCW）医学院的生理学系，它提供的研究培训强调在所有这些层次的知识与发展的这种知识的关系，以疾病过程的赞赏整合。根据目前的提议，我们将继续每年为六名NIH支持的受训人员提供细胞、分子和整个动物生理学方面的特殊培训。拟议培训的一个独特方面是指导计划，其中包括来自各种传统领域的基础科学家以及临床科学家。研究生将在全国范围内招募，并将根据本科学历，以前的研究经验和对研究事业的承诺进行选择。学生必须完成研究生院的第一年，然后才能被考虑用于NIH培训支持。学员的挑选将主要根据研究生院第一年的课程工作和研究实验室的表现。实习生为全日制博士。MCW生物医学科学研究生院的候选人。学员将完成必修和选修课程以及一个研究项目，其中包括使用分子生物学、分离组织和整个动物或临床研究技术。主要目标是为学员提供跨学科基础科学和转化研究的广泛基础。培训生将培养批判性思维，综合推理和创造和参与与预防和控制高血压，中风和呼吸系统疾病相关的不断发展的研究事业所需的技术技能。培训的一个创新特点是强调满足国家为后基因组时代生物医学研究的综合系统未来进行培训的需要。研究培训是在生理学教师的直接监督下，沿着与来自其他基础科学和临床部门的共同导师。学员和他们的导师将通过与项目主任和研究生委员会的一系列正式和非正式会议进行持续的进展评估。(End摘要）

DESCRIPTION (provided by applicant): Over the last twenty years, training in Physiology departments throughout the country has undergone a transformation that precludes students from a thorough understanding that spans the breadth of the discipline from the whole animal to the cellular and molecular level. An exception is the Physiology Department of the Medical College of Wisconsin (MCW), that offers research training emphasizing integration of knowledge at all of these levels with development of an appreciation for the relationship of this knowledge to disease processes. With the current proposal, we will continue providing this exceptional training in cellular, molecular, and whole animal Physiology for six NIH-supported trainees each year. A unique aspect of the proposed training is the mentoring program, which includes basic scientists from a variety of traditional areas as well as clinician scientists. Graduate students wll be recruited nationally and will be selected on the basis of undergraduate academic credentials, previous research experience, and commitment to a career in research. Students must complete the first year of graduate school before they will be considered for NIH training support. Selection of trainees will be based primarily on performance in course work and in the research laboratory during the first year of graduate school. Trainees are full-time Ph.D. candidates in the MCW Graduate School of Biomedical Sciences. Trainees will complete required and elective courses and a research project that includes use of the techniques of molecular biology, isolated tissues, and whole animal or clinical investigation. The major objective is to provide trainees with a broad foundation in interdisciplinary basic science and translational research. The trainee will develop the critical thinking, integrative reasoning, and technical skills required to create and participate in evolving research careers related to prevention and control of hypertension, stroke, and respiratory diseases. An innovative feature of the training is the emphasis on addressing the national need to train for the integrated-systems future of biomedical research in the post- genome era. Research training is under the direct supervision of Physiology faculty along with co-mentors from other basic science and clinical departments. Trainees and their mentors will undergo continuous evaluation of progress through a series of formal and informal meetings with the program director and the graduate committee. (End of Abstract)