Data Management and Statistics Core C

数据管理和统计核心提供统计咨询、数据管理和信息 调拨资源以提高ADRC进行的阿尔茨海默病研究的质量 调查人员。 具体目标是： 1.为核心和项目提供数据库支持。协调进场，质量控制， 门诊招生、评估、随访数据的管理与分析 和由中心临床核心招募的对照受试者。同样，为了协调条目，质量 控制、管理和分析由该中心的神经病理核心生成的数据。 2.准备ADRC数据库，以便常规提交给国家阿尔茨海默氏症协调中心 (NACC)。 3.为发改委调查人员提供统计设计和分析咨询服务。设计 咨询权计算和统计分析规划。数据分析支持范围从 为进行复杂的多变量统计分析提供简单的描述性统计。 4.开发新的统计方法，重点应用于阿尔茨海默病数据。 5.对调查人员、受训人员和初级教员进行统计分析原理和使用的教育 方法论。 相关性(请参阅说明)： 广告影响着数以百万计的美国人，其风险随着年龄的增长呈指数级增长。AD中心计划 促进与阿尔茨海默病和非阿尔茨海默病相关的研究。ADRC将加强以下方面的表现 关于AD和相关主题的创新研究，包括可能导致潜在疾病的研究 修改疗法或行为疗法。它将提供一个环境和核心资源，以加强 研究，促进专业和社区培训，协调跨学科研究。

The Data Management and Statistics Core provide statistical consulting, data management and information transfer resources to enhance the quality of Alzheimer's disease research conducted by the ADRC investigators. The specific aims are: 1. To provide database support to the Cores and Projects. To coordinate the entry, quality control, management and analysis of data generated by the enrollment, evaluation, and follow up of outpatient and control subjects recruited by the Centers Clinical Core. Similarly, to coordinate the entry, quality control, management and analysis of data generated by the Center's Neuropathology Core. 2. To prepare the ADRC database for routine submission to the National Alzheimer's Coordinating Center (NACC). 3. To provide statistical design and analysis consultation services to ADRC investigators. Design consultation power calculations and statistical analysis planning. Data analysis support ranges from providing simple descriptive statistics to the conduct of complex multivariate statistical analyses. 4. To develop new statistical methodology focused on application to Alzheimer's disease data. 5. To educate investigators, trainees and junior faculty in the principles and use of statistical analysis methodologies. RELEVANCE (See instructions): AD affects millions of Americans with its risk growing exponentially with age. The AD Centers Program fosters research related to AD and non-AD dementias. The ADRC will enhance the performance of innovative research on AD and related topics, including research that may lead to potential disease modifying therapies or behavioral treatments. It will provide an environment and core resources to enhance research, foster professional and community training, and coordinate interdisciplinary research.