Infectious Disease Training in Clinical Investigation

描述（由申请人提供）：T32项目“临床研究中的传染病培训”的主要目标是提供指导研究培训，为医师调查员在传染病领域的成功和富有成效的学术生涯做好准备。这个项目的基本原理是，由于在美国和全球范围内新出现和再出现的感染，这个领域继续见证着巨大的增长和新的挑战，为此需要新一代训练有素的临床研究人员。为了实现这一目标，明尼苏达大学医学院（及其医学院、儿科和微生物系）、公共卫生学院、药学院、牙科学院、兽医学院以及明尼苏达州卫生部的跨学科教师参与了这一培训计划。这些教师培训师在与新出现和再出现的感染相关的八个核心主题领域中的一个或多个方面具有专业知识：1)艾滋病毒/艾滋病，2)侵袭性细菌感染，3)抗菌素耐药性，4)免疫缺陷/疫苗，5)国际和移民健康，6)生物恐怖主义，7)食源性感染，8)人畜共患病。该计划是为完成内科或儿科住院医师计划，加上至少一年的成人或儿科传染病临床培训的医生设计的。它将支持在临床和/或流行病学研究方面进行为期两年的重点研究和密切指导的研究培训，并完成流行病学公共卫生硕士学位或临床研究理学硕士学位的要求。该项目每年将接受大约两名新学员，在任何时候，该项目总共约有四名学员。相关性（见说明）：这一培训方案的相关性在于新出现和再出现的感染对公众健康构成的威胁越来越大，例如社区相关的耐甲氧西林金黄色葡萄球菌、艾滋病毒/艾滋病流行、广泛耐药结核病、大肠杆菌0157:H7爆发、大流行性流感和禽流感。这就需要更多的专业临床研究人员，他们可以发现这些日益增长的威胁的原因，并找到补救措施。

DESCRIPTION (provided by applicant): The principal objective of the T32 program "Infectious Disease Training in Clinical Investigation" is to provide mentored research training that will prepare physician investigators for successful and productive academic careers in Infectious Diseases. The rationale for this program is that this field continues to witness enormous growth and new challenges due to emerging and re-emerging infections, both within the U.S. and globally, for which a new generation of well-trained clinical investigators is needed. To accomplish this goal, an interdisciplinary faculty from the University of Minnesota Medical School (and its Departments of Medicine, Pediatrics, and Microbiology), School of Public Health, College of Pharmacy, College of Dentistry, and College of Veterinary Medicine, as well as the Minnesota Department of Health, has been engaged in this training program. These faculty trainers have expertise in one or more of eight core topic areas relevant to emerging and re-emerging Infections: 1) HIV/AIDS, 2) Invasive Bacterial Infections, 3) Antimicrobial Resistance, 4) Immunodeficiency/Vaccines, 5) International and Immigrant Health, 6) Bioterrorism, 7) Foodborne Infections, and 8) Zoonoses. The program is designed for physicians who have completed an internal medicine or pediatrics residency program, plus at least one year of clinical training in adult or pediatric Infectious Diseases. It will support two years of focused, closely mentored research training in clinical and/or epidemiological research, as well as completion of the requirements for a Master of Public Health in Epidemiology or Master of Science in Clinical Research degree. The program will accept approximately two new trainees annually, giving a total of approximately four trainees in the program at any time. RELEVANCE (See instructions): The relevance of this training program lies in the increasing threat to public health posed by emerging and re-emerging infections, as exemplified by community-associated methicillin-resistant Staphylococcus aureus, the HIV/AIDS epidemic, extensively-drug-resistant tuberculosis, E. coli 0157:H7 outbreaks, and pandemic and avian influenza. This has created a need for additional expert clinical researchers who can discover the causes of, and find remedies for these growing threats.