Transcriptome analysis of Phytophthora–plant interactions: characterisation of plant inhibitor proteins targeting Phytophthora extracellular effectors

植物防御的一个重要方面是保护植物细胞壁免受病原体入侵。植物通过特定针对病原体细胞壁降解酶的抑制剂的活性来实现这一点。这些抑制蛋白在工程改良植物抗病方面有很大的潜力，但由于对它们的部署和特异性的了解有限，它们的使用受到了阻碍。该项目将深入了解植物抑制物的身份、调节和作用，这些植物抑制物可对抗疫霉属破坏性病原体的攻击。它不仅将解决澳大利亚严重的疫病问题，还将适用于植物抵御其他病原体的防御。

A critical aspect of plant defence is protection of plant cell walls against pathogen penetration. Plants achieve this through the activity of inhibitors that specifically target pathogen cell wall degrading enzymes. These inhibitor proteins have great potential in engineering improved plant resistance to disease but their use is hampered by limited knowledge of their deployment and specificity. This project will produce an in-depth understanding of the identity, regulation and role of plant inhibitors that combat attack by destructive pathogens in the genus Phytophthora. It will not only address the serious problem of Phytophthora diseases in Australia but will also apply to plant defence against other pathogens.