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中文摘要
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五岁育龄妇女,包括青春期女孩、怀孕二、三个月的妇女, 哺乳期妇女是土壤传播蠕虫致病的高危人群, 主要是鞭虫和钩虫感染。世卫组织,除其他全球、区域和国家外 组织建议在流行地区针对这一群体进行大规模驱虫 钩虫感染率超过20%。我们提出的研究将提供经验证据,以供 指导针对这一风险的大规模驱虫计划的卫生政策和计划实施 一群人。确定了四个目标:1)对无意中暴露于 怀孕前三个月驱虫;2)评估在校青春期女孩的接受能力- 回答有关怀孕的问题的年龄(排除在以学校为基础的前三个月期间驱虫 驱虫计划);3)确定妇女第一次参加产前检查的怀孕阶段 保健诊所;以及4)确定驱虫对母亲和婴儿的健康影响 住院妇女,分娩后立即死亡。这项研究的结果将有助于确保- 以育龄妇女为目标的有效和高效的驱虫方案,最终 减轻这一脆弱人群中蠕虫感染的疾病负担。 相关性(请参阅说明): 生殖五岁的妇女在很大程度上被驱虫计划忽视了,尽管她们是 推荐驱虫的三个高危人群(主要是由于鞭虫引起的贫血 和钩虫感染)。这可能是因为一些研究空白限制了健康的发展。 这一领域的政策和计划管理。因此,拟议的研究涉及四个重要的问题 令人担忧。‘;在行政管理中。
英文摘要
Women of reproducfive age, including adolescent girls, pregnant women in their second or third trimester, and lactating women constitute a high-risk group for morbidity attributable to the soil-transmitted helminths, primarily Trichuris and hookworm infections. WHO, among other global, regional and national organizafions, recommends mass deworming targeted to this group in endemic areas where the prevalence of hookworm infection exceeds 20%. The research we propose will provide empirical evidence on which to guide health policy and program implementafion for large-scale deworming programs targefing this at-risk group. Four objecfives are identified: 1) to conduct a systemafic review of inadvertent exposure to deworming in the first trimester of pregnancy; 2) to assess the receptiveness of adolescent girls of school- age to answer quesfions on pregnancy (to rule out deworming during the first trimester during school-based deworming programs); 3) to determine the stage of pregnancy at which women will first attend an antenatal care clinic; and 4) to determine the health impact, to mothers and babies, of deworming administered to women in-hospital, immediately after delivery. The results of this research will contribute to ensuring cost- effective and efficient deworming programs targeted to women of reproductive age and, ulfimately, to reducing the disease burden of helminth infection in this vulnerable population. RELEVANCE (See instmctions): Women of reproducfive age have largely been neglected by deworming programs despite being one of the three most at-risk groups for which deworming is recommended (primarily due to anemia caused by Trichuris and hookworm infections). This may be because several research gaps limit the development of health policy and program management in this area. The proposed research therefore addresses four important concern.'; stjrroijndina thft administratir^n nf dewnrnninn rinjo.s in adnlfi.
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Data and Biostatistics
Improving Childhood Growth and Development in Resource-Poor LMICs with Deworming
Assessing Deworming Programs Targeted to Adolescent and Adult Women
Data and Biostatistics
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