Everyday Discrimination and Cardiovascular Disease in African-American Women

描述(由申请人提供)： 这位候选人是一名心理学家，也是耶鲁大学医学院流行病和公共卫生系的新助理教授。她的长期职业目标是在心理社会流行病学领域建立一个独立的研究计划，重点是非裔美国女性的心血管疾病(CVD)。本申请中描述的综合研究和培训计划扩展了她之前在心理学和非裔美国女性健康方面的工作，并纳入了以下方面的新培训：1)流行病学和生物统计学；2)心血管生理学；3)研究设计和实施；以及4)最先进的心理评估技术。在这项科学家指导职业发展奖中提出的研究利用多种方法来确定自我报告的“日常”歧视经历是否与两个不同的非裔美国女性队列中的心血管疾病指数显著相关。研究计划描述了三个独立但相互关联的项目，旨在审查拟议的日常歧视和心血管疾病协会。所采用的方法包括：二次数据分析、初级数据收集和生态瞬时评估。拟议的职业发展计划将发展和增强候选人的知识基础、技能和专业知识，拟议研究的结果将为一项研究项目奠定基础，该项目旨在研究非裔美国女性心血管疾病预后不良的心理社会预测因素。拟议研究的重要进展是将心理社会概念严格应用于疾病模式的研究，并具体评估了一种常见的心理社会应激源(即“日常”歧视)的影响，而对其公共健康影响的研究还不够深入。(摘要结束)

DESCRIPTION (provided by applicant): The Candidate is a Psychologist and a new Assistant Professor in the Department of Epidemiology and Public Health at the Yale University School of Medicine. Her long-term career objective is to establish an independent program of research in the area of psychosocial epidemiology, with an emphasis on cardiovascular disease (CVD) in African-American women. The integrated research and training program described in this application extends her prior work in Psychology and African-American women's health, and incorporates new training in: 1) Epidemiology and Biostatistics; 2) Cardiovascular Physiology; 3) Study design and implementation; and 4) State-of-the-art Psychological Assessment techniques. The research proposed in this Mentored Scientist Career Development Award utilizes a multi-method approach to determine whether self-reported experiences of "everyday" discrimination are significantly associated with indices of CVD in two separate cohorts of African-American women. The research plan describes three separate but interrelated projects designed to examine the proposed everyday discrimination and CVD association. Methodologies employed include: Secondary data analysis, primary data collection, and Ecological Momentary Assessment. The proposed career development plan will develop and enhance the Candidate's knowledge base, skills, and expertise, and findings from the proposed studies will lay the foundation for a program of research examining the psychosocial predictors of poor CVD outcomes in African-American women. Important advancements in the proposed research are the rigorous application of psychosocial constructs to the study of patterns of disease, and the specific evaluation of the impact of a common psychsocial stressor (i.e., "everyday" discrimination) that is understudied in terms of its public health impact. (End of Abstract)