Colorado Clinical and Translational Sciences Institute

当今医学面临的最大挑战之一是高效、无缝和安全地翻译生物医学信息。 将研究发现转化为临床应用，改善人类健康。新方法、新技术 和综合信息系统提供了前所未有的承诺，发现和增长的翻译 成功;然而，重大障碍继续困扰着我们迅速将发现转移到 临床实践，包括我们的研究过程的效率，成本和效果。科罗拉多号 成立于2008年的临床和转化科学研究所（CCTSl）已经解决了这些挑战， 改变了我们的机构研究基础设施。在这份申请中，科罗拉多丹佛大学 （CU-D）和我们的合作机构（CU-Boulder和科罗拉多州立大学[CSU]，六家主要医院 和卫生保健组织和当地社区）将通过以下五个方面重新设计CCTSl 战略目标：1）丰富和扩大我们的综合全州学术家临床和翻译 research. 2)制定新的临床研究管理战略，以加强质量、安全、效率， 成本效益和创新的团队科学，包括实施新的软件系统和工作 流动。3)集中和加强我们优秀的资源、服务和技术的交付， 在适当情况下向调查人员收费。4)融入社区参与的关键概念 转化研究的全方位。5)提高翻译研究队伍的能力 通过广泛的教育、培训和职业发展机会课程。严格的跟踪， 与正式的质量和过程改进计划相结合的评估和评价计划 嵌入CCCTSl将确保最有效，最具成本效益和创新地使用我们宝贵的 在保护我们的研究参与者的安全的同时。这些计划将集中在一个 美国最新的生物医学研究，教育和临床企业，CU Anschutz Medical 校园内毗邻我们的学校，研究实验室，三家医院和一个生物医学 企业园区为我们的成功创造了理想的环境。 相关性（参见说明）： 这个项目与公共卫生的相关性在于我们有能力帮助研究人员把重要的发现 并将其转化为人类疾病的新疗法，预防和治疗。我们也会帮助 研究人员找到了将这些疗法带入社区环境的方法， 和国家。

One of medicine's greatest challenges today is the efficient, seamless and safe translation of biomedical research discoveries into clinical applications that improve human health. New methodologies, technologies and integrated information systems offer unprecedented promise for discovery and growth of translational successes; however significant barriers continue to confound our ability to rapidly move discoveries into clinical practice, including the efficiency, cost and effectiveness of our research processes. The Colorado Clinical and Translational Sciences Institute (CCTSl), created in 2008, has addressed these challenges and transformed our institutional research infrastructure. In this application, the University of Colorado Denver (CU-D) and our partner institutions (CU-Boulder and Colorado State University [CSU], six major hospitals and health care organizations and local communities) will re-engineer the CCTSl through the following five Strategic Goals: 1) Enrich and expand our integrated statewide academic home for clinicaland translational research. 2) Institute new clinical research management strategies to strengthen quality, safety, efficiency, cost effectiveness and innovative team science, including implementing new software systems and work flows. 3) Centralize and enhance the delivery of our outstanding resources, services and technologies and institute charge-backs to investigators where appropriate. 4) Infuse key concepts of community engagement into the full spectrum of translational research. 5) Increase the translational research workforce capacity through a broad curriculum of education, training and career development opportunities. A rigorous tracking, assessment and evaluation program coupled to a formal quality and process improvement program embedded in the CCCTSl will ensure the most efficient, cost-effective, and innovative use of our precious resources, while protecting the safety of our study participants. These programs will be centralized at one of the newest biomedical research, education and clinical enterprises in the nation, the CU Anschutz Medical Campus in which adjacencies of our schools, research laboratories, three hospitals and a biomedical corporate park create the ideal environment for our success. RELEVANCE (See instructions): The relevance of this project to public health lies in our ability to help researchers take important discoveries and translate them into new treatments, preventions and cures for human diseases. We also will help researchers find ways to bring these therapies into the community setting to benefit people across our state and country.