Integrated basic and clinical cardiovascular research for the development of innovative approaches to the treatment of heart failure

心力衰竭（HF）是一种常见的心血管疾病，它会导致致残症状并降低预期寿命。心衰是65岁以上人群住院的最常见原因或原因。晚期心衰患者的生存率比侵袭性癌症患者差。目前，对于晚期心衰及其并发症的患者，治疗方案很少。在接下来的5年里，我将在动物模型和患者身上进行一系列全面的研究，以开发新的治疗方案。

Heart failure (HF) is a common cardiovascular problem which causes disabling symptoms and reduces life expectancy. HF is the commonest cause or contributor to hospitalization in people over 65 years. For patients with advanced HF, survival is worse than that for aggresive cancers. At present, for patients with advanced HF and its complications, there are very few treatment options. Over the next 5 years I will conduct a comprehensive series of studies in animal models and in patients to develop new treatment options.