Biostatistics Core

该计划项目拨款的生物统计核心负责开发和执行满足该计划项目拨款中每个单独项目的目标所需的大型和小规模统计分析。这涉及： (1) 为每个项目选择适当的统计方法和软件，并在必要时开发与所选方法的实施相关的附加软件。在某些情况下，这还可能包括开发新的统计方法 (2) 为项目申请中的每个项目设计和开发分析文件。这包括协助从多种族队列 (MEC) 生物样本库中选择用于项目 1 - 4 研究的分析样品，并参与质量控制数据的设计和分析，以确定实验室变异以及所有项目中与吸烟相关的生物标志物之间和人体内的变异(3) 使用 (2) 中的分析文件对每个项目执行和/或指导数据分析。

The Biostatistics Core for this program project grant is responsible for developing and performing the large and small scale statistical analysis required for meeting the aims of each of the individual projects in this program project grant. This involves: (1) Choosing appropriate statistical methods and software for each project and when necessary developing additional software relating to the implementation of the selected methods. In some cases this may also include development of new statistical methods (2) Designing and developing analysis files for each of the projects in the program project application. This includes assisting in the selection of samples for analysis from the Multiethnic Cohort (MEC) biorepository for study in Projects 1 - 4 , and participating in the design and analysis of quality control data to determine laboratory variation, and between and within person-variation in the smoking-related biomarkers of concern in all projects(3) Performing and/or guiding data analysis for each project using the analysis files from (2).